Imidazole alkaloids from Lepidium meyenii and methods of usage

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S396000

Reexamination Certificate

active

06878731

ABSTRACT:
The present invention relates to novel imidazole alkaloid compounds that have been isolated as a form of chloride salt from a root extract ofLepidium meyeniiWalp, with the common name Maca, and identified below as 1,3-bis(phenylmethyl)-4,5-dimethyl-1H-imidazlium chloride and 1,3-bis(phenylmethyl)-2,4,5-trimethyl-1H-imidazlium chloride, compounds (1) and (2), respectively.The present invention further relates to the use of these novel compounds (1) and (2) to treat proliferative diseases, such as but not limited to cancer.

REFERENCES:
patent: 4481211 (1984-11-01), Dockner et al.
patent: 4605661 (1986-08-01), Hirsch et al.
patent: 4916144 (1990-04-01), Strehlke et al.
Internal Medicine, 4th Edition, Editor-in-Chief Jay Stein, Chapters 71-72, pp. 699-715.

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