Retroviral protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514533, 514542, 514563, 514616, 560 29, 560 39, 562448, 564158, 558392, A61K 3119, C07C23377

Patent

active

056021755

ABSTRACT:
Hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

REFERENCES:
patent: H725 (1990-01-01), Gordon
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5132400 (1992-07-01), Gammill et al.
patent: 5151438 (1992-09-01), Sham et al.
patent: 5157041 (1992-10-01), Handa et al.
Roberts et al, Science, 248, 358 (1990).
Erickson et al, Science, 249: 527-533 (1990).
Krohn et al, J. Med. Chem., 34, 3340 (1991).
Drugs of the Future, (1991) 16(3), 210-212.
Meek et al, Nature, 343: 90-92, (1990).
McQuade et al, "A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle Maturation", Science, 274, 454 (1990).
Pept. Struct. Funct. Proc. Am. Pept. Sym. 8th ed. by V. J. Hunby and D. H. Rich, pp. 511-520 (1983).
Rosenberg et al, J. Med. Chem., 30, 1224-1228 (1987).
Fittkau, J. Prakt. Chem. 315, 1037-1044 (1973).
Plattner et al, J. Med. Chem., 31, 2277-88 (1988).
Bolis et al, J. Med. Chem., 30, 1729-37 (1987).
Denkewalter et al, "Progress in Drug Research", 10, 510-12 (1966).
A. Burger, Med. Chem., 2nd Ed., 565-601 (1960).
Haber et al, J. Cardiovasc. Pharmacol, 10, 7, 54-57 (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Retroviral protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retroviral protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retroviral protease inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-342667

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.