Tricyclic compounds useful for inhibition of G-protein function

Details Tricyclic compounds useful for inhibition of G-protein function Tricyclic compounds useful for inhibition of G-protein function

1995-04-07

1998-01-27

McKane, Joseph

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 5142278, 5142282, 5142328, 5142355, 544 60, 544121, 544360, 544361, 544380, A61K 31495, C07D40106

Patent

active

057122806

ABSTRACT:
Novel compounds of Formula ##STR1## are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the Formula 1.0 to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

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