Oxazolidinone photoaffinity probes

Details Oxazolidinone photoaffinity probes Oxazolidinone photoaffinity probes

2005-04-05

2005-04-05

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S272100

Reexamination Certificate

active

06875871

ABSTRACT:
Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.

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Matassova, et al., “Ribosomal RNA is the target for oxazolidinones, a novel class of translation inhibitors,” RNA (1999) 5:939-946.
Porse et al, “Direct crosslinking of the antitumorantibiotic sparsomycin, and its derivatives, to A2602 in peptidyl transferase center of 23S-like rRNA within tRNA complexes,” Proc. Natl. Acad. Sci. USA (1999) 96:9003-9008.

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