Pyridobenzo- and pyridiothieno-diazepines useful for the treatme

Details Pyridobenzo- and pyridiothieno-diazepines useful for the treatme Pyridobenzo- and pyridiothieno-diazepines useful for the treatme

1994-12-29

1997-02-11

Datlow, Philip I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514220, 540542, 540557, A61K 3155, C07D47104, C07D49514

Patent

active

056021135

ABSTRACT:
Disclosed are novel pyrido[2,3,-b][1,5]benzodiazepines. These compounds are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection. ##STR1##

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J. Benditt and J. Cohen, Science, vol. 260, May 28, 1993, pp. 1253-1255.
Sandstrom et al., Review Article in Drugs, 34, pp. 373-390 (1987).
Yarchoan et al, AIDS: Modern Concepts and Therapeutic Challanges, Marcel Dekker Inc. pp. 335-360 (1987).
Hahn et al, "Nucleotide Dimers as Anti-Human Immuno-deficiency Virus Agents," in Nucleotide Analogues as Antiviral Agents, Martin ed, Amer. Chem. Soc., pp. 156-159 (1989).
March, Advanced Organiz Chem., 3rd ed. (1985), pp. 527-529.

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