Human secreted protein HTEEB42

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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Details

C530S350000, C530S300000, C435S007100, C435S069100, C435S325000, C435S320100, C514S002600, C514S012200, C514S021800

Reexamination Certificate

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06878806

ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

REFERENCES:
patent: WO-9914241 (1999-03-01), None
patent: WO-9927098 (1999-06-01), None
patent: WO-0015797 (2000-03-01), None
Cunningham et al., “A novel protein with homology to the junctional adhesion molecule,”J. Biol. Chem. 275(44):34750-24756 (2000).
Cunningham et al., “JAM2 Interacts with α4β1,”J. Biol. Chem. 277(31):27589-27592 (Aug. 2, 2002).
Palmeri et al., “Vascular Endothelial Junction-associated Molecule, a Novel Member of the Immunoglobulin Superfamily, Is Localized to Intercellular Boundaries of Endothelial Cells,”J. Biol. Chem. 275(25):19139-19145 (Jun. 23, 2000).
Liang et al., “Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3,”J. Immunol. 168:1618-1626 (2002).
GenBank Accession No. AL570767, Li et al., “AL57067Homo sapiensPLACENTA COT 25-NORMALIZEDHomo sapienscDNA clone CS0DI022YK04 3-PRIME, mRNA sequence” (May 31, 2003).
GenBank Accession No. N90730, Hillier et al., “za90e09.s1 Soares_fetal_lung_NbHL 19WHomo sapienscDNA clone IMAGE:299848 3′, mRNA sequence” (Apr. 3, 1996).
GenBank Accession No. T89217, Hillier et al., “ye12c02.r1 Stratagene lung (#937210)Homo sapienscDNA clone IMAGE:117506 5′, mRNA sequence” (Mar. 20, 1995).
GenBank Accession No. AI556456, Bonaldo et al., “UI-R-C2p-rh-g-10-0-UI.s1 UI-R-C2p Rattus norvegicus cDNA clone UI-R-C2p-rh-g-10-0-UI 3′, mRNA sequence” (Jul. 5, 1999).
GenBank Accession No. AA410345, Hillier et al., “zv12a02.s1 Soares_NhHMPu_S1Homo sapienscDNA clone IMAGE:753386 3′, mRNA sequence” (May 17, 1997).
GenBank Accession No. BE653351, Bonaldo et al., “UI-M-AL1-ahi-d-06-0-UI.r1 NIH_BMAP_MCO_NMus musculuscDNA clone UI-M-AL1-ahi-d-06-0-UI 5′, mRNA sequence” (Sep. 6, 2000).

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