Cell line TriH8 obtained by the fusion of the human epidermoid c

Details Cell line TriH8 obtained by the fusion of the human epidermoid c Cell line TriH8 obtained by the fusion of the human epidermoid c

1992-12-16

1997-02-11

Adams, Donald E.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

435346, C12N 512, C12N 524

Patent

active

056020279

ABSTRACT:
A new cell line TriH8 is obtained by fusing a particular sub-clone, A431c, of the human epidermoid carcinoma cell line A431 with the TOS/H8 (human/human) hybridoma. Fused cell TriH8 has been deposited under FRI accession number FERM BP-4452. The fused cell is capable of proliferating in basal medium without addition of serum or growth factor. The cell line is more effective in producing antibody (IgM) than the donor cell TOS/H8.

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Aotsuka et al. Cell Immunol. 133(2):498-505 (1991).
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