Polymorphisms in known genes associated with inflammatory...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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Details

C435S091200, C435S320100, C530S350000, C536S023400

Reexamination Certificate

active

06900016

ABSTRACT:
The present invention is based on the discovery of novel polymorphisms (SNPs) in the genes known in the art to contribute to inflammatory and autoimmune disorders. Such polymorphisms can lead to a variety of disorders that are mediated/modulated by a variant inflammatory and autoimmune disorders associated protein. The present invention provides reagents used for detecting and expressing the variant nucleic acid/protein sequence as well as methods of identifying and using these variants.

REFERENCES:
Genebank entry for gi: 15718696 (NM_001227).
Genebank entry for gi: 4502581 (NM_001218).
OMIM entry for Caspase 7 (omim No. 601761).

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