DNA encoding a human dopamine D1 receptor and uses thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C436S501000

Reexamination Certificate

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06939680

ABSTRACT:
This invention provides isolated nucleic acid molecules encoding a human dopamine D1receptor, isolated proteins which are human dopamine D1receptor, vectors comprising isolated nucleic acid molecules encoding a human dopamine D1receptor, mammalian cells comprising such vectors, antibodies directed to a human dopamine D1receptor, nucleic acid probes useful for detecting nucleic acid encoding human dopamine D1receptor, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human dopamine D1receptor, pharmaceutical compounds related to human dopamine D1receptor, and nonhuman transgenic animals which express DNA a normal or a mutant human dopamine D1receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving a human dopamine D1receptor.

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