Purification method and apparatus

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Treating animal or plant material or micro-organism

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S006120, C435S287200, C435S287900, C436S094000, C536S023100, C422S051000, C422S051000, C422S091000

Reexamination Certificate

active

06919200

ABSTRACT:
A purification apparatus, kit and method for purifying DNA, RNA, proteins, antigens, antibodies and cells. The apparatus has a wand and a reservoir tube. The wand is made of a cap, a sample collection assembly and an elongated shaft connecting the cap to the sample collection assembly. The sample collection assembly has a series of microstructures on its surface, or microparticles enclosed within it for increasing the surface area of the sample collection assembly. The increased surface area permits maximum exposure to and binding of target molecules thereto. The reservoir tube associated with the wand has one end defining an opening and a second end that is closed and preferably cone or cylindrical shaped. The cap of the wand securely and sealingly fastens to the open end of the reservoir tube with the shaft and the sample collection assembly fitting easily inside the reservoir tube. The apparatus, kit and methods can be used for protein and nucleic acids detection by calorimetric, luminescent, fluorescent or electrochemical means through attachments for detecting such signals. The apparatus, kit and methods can also be used in conjunction with an attachment for thermal regulation to perform nucleic acids amplification. The apparatus, kit and methods can further be configured for integrated, high throughput purification and detection of proteins and nucleic acids.

REFERENCES:
patent: 4225575 (1980-09-01), Piasio et al.
patent: 4657869 (1987-04-01), Richards et al.
patent: 4789628 (1988-12-01), Nayak
patent: 5173260 (1992-12-01), Zander et al.
patent: 5229297 (1993-07-01), Schnipelsky et al.
patent: 5483972 (1996-01-01), Nabai et al.
patent: 5514785 (1996-05-01), Van Ness et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5591841 (1997-01-01), Ji et al.
patent: 5637687 (1997-06-01), Wiggins
patent: 5665582 (1997-09-01), Kausch
patent: 5962218 (1999-10-01), Leland
patent: 6020186 (2000-02-01), Henco et al.
patent: 6228578 (2001-05-01), Impraim et al.
patent: 2003/0204077 (2003-10-01), Simms
patent: 0730814 (1995-11-01), None
patent: 7-308184 (1995-11-01), None
patent: 94/18564 (1994-08-01), None
patent: WO94 18564 (1994-09-01), None
patent: WO95 19447 (1995-07-01), None
Boom et al., Journal of Clinical Microbiology, Mar. 1990, vol. 28, No. 3, pp. 495-503.
Boom et al., “Rapid and Simple Method for Purification of Nucleic Acids,” Journal of Clinical Microbiology, Mar. 1990, vol. 28, No. 3, pp. 495-503.
Boom et al., “Rapid and Simple Method for Purification of Nucleic Acids,” Journal of Clinical Microbiology, Mar. 1990, vol. 28 No. 3, pp. 495-503.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Purification method and apparatus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification method and apparatus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification method and apparatus will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3404825

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.