Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-05-03
2005-05-03
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S336000, C514S366000, C514S570000, C514S563000, C514S469000, C514S406000, C514S562000, C514S438000, C514S400000, C514S378000, C514S375000, C514S461000, C514S326000, C562S450000, C562S430000, C548S204000, C548S224000, C548S247000, C548S248000, C548S335500, C548S338100, C548S370100, C546S209000, C546S281400, C549S077000, C549S469000, C549S493000, C544S369000
Reexamination Certificate
active
06887877
ABSTRACT:
The present invention provides novel compounds represented by formula I:or pharmaceutically acceptable salts thereof useful for treating Flaviviridae viral infection.
REFERENCES:
patent: 5977075 (1999-11-01), Ksander et al.
patent: 6174877 (2001-01-01), Ishibashi et al.
patent: 2305499 (1998-09-01), None
patent: 3-127732 (1991-05-01), None
patent: 7-48360 (1995-02-01), None
patent: 7-48360 (1995-06-01), None
patent: 2000-159610 (2000-06-01), None
patent: 2 130 023 (1999-05-01), None
patent: WO 9112002 (1991-08-01), None
patent: WO 9512611 (1995-05-01), None
patent: WO 9638419 (1996-12-01), None
patent: WO 9803166 (1998-01-01), None
patent: WO 0003743 (2000-01-01), None
patent: WO 0015213 (2000-03-01), None
patent: WO 0037436 (2000-06-01), None
patent: WO 0120995 (2001-03-01), None
patent: WO 01-20995 (2001-03-01), None
Douglas, Jr., Introduction to Viral Diseases, Cecil Textbook of Medicine, 20thEdition, vol. 2, pp. 1739-1747, 1996.*
DeFonseca et al., PubMed Abstract (Curr Opin Pediatr. 14(1):67-71), Feb. 2002.*
Sehgal et al., PubMed Abstract (Indian J. Pathol. Microbiol. 45(1):123-8), Jan. 2002.*
Fabrizi et al., PubMed Abstract (Perit Dial Int. 22(3):405-10), May 2002.*
Lindsay, PubMed Abstract (Hepatology 36(5 Suppl 1):S114-20), Nov. 2002.*
Scozzafava et al., CAPLUS Abstract 132:344757, 2000.*
Supuran et al., CAPLUS Abstract 133:177439, 2000.*
Budesinsky et al., CAPLUS Abstract 54:6563f-i, 6564a-g, 1960.*
Anette Svenson, et al., “Preparation of Fluorniated Linkers: Use of19F NMR Spectroscopy to Establish Conditions for Solid Phase Synthesis of Pilicide Libraries”,J. Comb. Chem. 2000, vol. 2, pp. 736-748.
Gregory T Bourne et al., “A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1”,J. Org. Chem. 1999, vol. 64, pp. 3095-3101.
Carceller et al. “Novel Azo Derivatives as Prodrugs of 5-Aminosalicyclic Acid and Amino Derivatives with Potent Platelet Activating Factor Antagonist Activity”, Journal of Medicinal Chemistry, 2001, vol. 44, No. 18., pp. 3001-3013.
F. Dasgupta et al., “Peptoids as Endothelin Receptor Antagonists”, Bioorganic & Medicinal Chemistry Letters 11 (2001) pp. 555-557.
J. Piró et al., “Solid Phase Synthesis of Enantiomerically pure Polyhydroxyvalerolactams”, Tetrahedron Letters 42 (5) (2001) pp. 871-873.
A. Svensson, “Preparation of Fluorinated Linkers: Use of19F NMR Spectroscopy to Establish Conditions for Solid-Phase Synthesis of Pilicide Libraries”, Journal of Combinatorial Chemistry, 2000, vol. 2, No. 6, pp. 736-748.
Lin et al., “Utilization of Fukuyama's Sulfonamide Protecting Group for the Synthesis of N-substituted α-amino acids and Derivatives”, Tetrahedron Letters 41 (18) (2000) pp. 3309-3313.
Turner et al., “Mitsunobu Glycosylation of Nitrobenzenesulfonamides: Novel Route to Amadon Rearrangement Products”, Tetrahedron Letters 40 (38) (1999) pp. 7039-7042.
Caldarelli et al., “Synthesis of an Array of Potential Matrix Metalloproteinase Inhibitors using a Sequence of Polymer-Supported Reagents”, Bioorganic & Medicinal Chemistry Letters 9 (14) (1999) pp. 2049-2052.
Donde et al., “High Enantioselection in the Rearrangement of Allylic Imidates with Ferrocenyl Oxaoline Catalysts”, J. American Chemical Society, 1999, vol. 121, No. 12, pp. 2933-2934.
Wilson et al., “A Facile Rearrangement of N-Alkyl, N-(0 or p-NitrophenylSulfonamide)-α-Amino Esters”, Tetrahedron Letters 55 (6) (1999) pp. 1647-1656.
Kawase et al., “A General Method for the Preparation of 5-Trifluoromethylated Oxazoles from α-Amino Acids”, Chemical Pharmaceutical Bulletin 46(5) (May, 1998) pp. 749-756.
Reichwein et al., “Site-Specific N-Alkylation of Peptides on the Solid Phase”, Tetrahedron Letters 39 (10) (1998) pp. 1243-1246.
Fukuyama et al., “2,4-Dinitrobenzenesulfonamides: A Simple and Practical Method for the Preparation of a Variety of Secondary Amines and Diamines”, Tetrahedron Letters, vol. 38, No. 33, pp. 5831-5834 (1997).
Masami Kawase, “A Facile One-Pot Synthesis of 5-Trifluoromethyl- and 5-Perfluoroalkyloxazoles from N-Alkyl-N-Acylamino Acids”, Heterocycles, vol. 36, No. 11, pp. 2441-2444, (1993).
Naito et al., “A New Synthesis of 2-amino-γ-Lactones Involving Photochemical Addition Reaction of Alcohols to Enamide”, Heterocycles, vol. 27, No. 6, pp. 1325-1327 (1988).
Gellert et al., “Stereospecific Synthesis of Hexahydrobenzopyrroloisoquinoline and Tetrahydrobenzisoquinoline Derivatives”, American Journal Chemistry, 1984, vol. 37, pp. 819-829.
Yoshioka et al., “Synthesis of Oxazolylindole Alkaloids from Tryptamine and Tryptophan by Oxidation with 2,3-Dichioro-5,6-dicyanobenzoquinone”, J. Chemical Research (S), 1981, pp. 194-195.
Hitchings et al., “Degradation of the Herbicide Flamprop-isopropyl in Soil under Laboratory Conditions”, Society of Chemical Industry, (1979) vol. 10, pp. 1-13.
Aida El Azzouny et al., “Zur Synthesis Acyclischer und Cyclischer Anthranilsäure-Phenylalanin-Peptide”, Pharmazie 32, H. 6 (1977), pp. 318-323.
Bourne et al., A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin, J. Org. Chem., 64(9), pp.: 3095-3101 (1999).
Dankwardt et al., “Solid-Phase Synthesis of N-alkyl Sulfonamides”, Synlett, (1997) (7), pp. 854-856.
Xiao et al., “Diastereoselective Synthesis of Drugs: Preparation of (S,S)-2hydroxy-3-amino-4-phenylbutyric Acid”, Huaxue Shijii, (1996), 18(6), pp. 324-326, 336.
Ru et al., “Diastereoselective Synthesid of (2S, 3S)-3-amino-2hydroxy-4-phenylbutyic acid: Core Unit of HIV Protease Inhibitors”, Zhongguo Yigao, Gongye Zahi, (1994), 25(12), pp. 557-559.
Bedard Jean
Chan Chun Kong Laval
Das Sanjoy Kumar
Nguyen Ba Nghe
Pereira Oswy Z.
Millen White Zelano & Branigan P.C.
ViroChem Pharma Inc.
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