Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1977-04-04
1978-07-18
Turner, V. D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
71 94, 71 67, 252390, 252 855R, 252 855E, 252 855D, 162161, A01N 936
Patent
active
041016548
ABSTRACT:
Quaternary nitrogen-heterocyclic phosphonates wherein the phosphonate group is ortho- or para- to the nitrogen heterocyclic group, where the compounds are characterized as follows: ##STR1## WHEREIN THE DOTTED LINE REPRESENTS A CYCLIC STRUCTURE WHICH CYCLIC STRUCTURE MAY BE THE SOLE CYCLIC STRUCTURE, OR MAY BE ATTACHED TO OTHER CYCLIC GROUPS, WHERE R is a hydrocarbon or a substituted hydrocarbon group such as alkyl, aryl, alkaryl, aralkyl, etc., and X is an anion such as halogen, a sulfite, a sulfate, s sulfonate-containing group, etc.
These nitrogen-heterocyclic phosphonates are prepared by reacting an aromatic nitrogen-heterocyclic compound, wherein the nitrogen atom is in the form of a quaternary alkoxy derivative (N-OR hereinafter defined) with a phosphite salt, preferably in the form of an ester of the phosphite, as exemplified by the following equation: ##STR2## Quaternaries of these compounds are prepared by further reaction with a quaternizing agent.
These compounds which may be characterized as quaternaries of phosphonates of nitrogen-heterocyclics have many uses including their use as biocides, such as bacteriocides, herbicides, corrosion inhibitors, chelating agents, etc.
REFERENCES:
patent: 3255078 (1966-06-01), Heinroth et al.
patent: 3318768 (1967-05-01), Young et al.
patent: 3673196 (1972-06-01), Redmore
patent: 3770750 (1973-11-01), Redmore
Glass Hyman F.
Petrolite Corporation
Ring Sidney B.
Turner V. D.
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