Pepstatin floating minicapsules

Details Pepstatin floating minicapsules Pepstatin floating minicapsules

1977-04-06

1978-07-18

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

424 14, A61K 946, A61K 950, A61K 3764

Patent

active

041016505

ABSTRACT:
Increased duration of inhibition of secretion of pepsin in man by oral administration of pepstatin is achieved by the use of a formulation in which pepstatin is coated on very small granules of sodium bicarbonate to form floating minicapsules.

REFERENCES:
patent: 536155 (1895-03-01), Noyes
patent: 2125577 (1938-08-01), Matsumae
patent: 2540253 (1951-02-01), Gakenheimer
patent: 3131123 (1964-04-01), Masquelier
patent: 3136692 (1964-06-01), Bandglin
patent: 3418999 (1968-12-01), Davis
patent: 3444290 (1969-05-01), Wai
patent: 3740319 (1973-06-01), Umezawa et al.
patent: 3887700 (1975-06-01), Boncey et al.
patent: 4036228 (1977-07-01), Theeunbs

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