Anti-fungal pharmaceutical compositions comprising an active...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from zingiberaceae

Reexamination Certificate

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Details

C424S074000, C424S773000, C514S864000

Reexamination Certificate

active

06946153

ABSTRACT:
A method of treating a patient suffering a disease associated withTrichophyton mentagrophytesorPityrosporum ovaleby applying topically an anti-fungal pharmaceutical composition which is prepared fromZingiber officinale, includes the following steps: preparing a crude liquid from rhizomes of ginger by extraction with an organic solvent or supercritical CO2, or by distillation with steam; introducing the crude liquid to a reverse phase chromatography column, and eluting the column with water, a first eluent and a second eluent having a polarity weaker than that of the first eluent but stronger than that of chloroform, so that a first eluate resulting from elution of the first eluent and a second eluate resulting from elution of the second eluent are obtained; removing the first eluent and the second eluent from the first eluate and the second eluate by evaporation, respectively, so that a first concentrated eluate and a second concentrated eluate are obtained as the potent extract.

REFERENCES:
patent: 6274177 (2001-08-01), Wu et al.

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