Process for the separation of...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091200, C536S023100

Reexamination Certificate

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06946250

ABSTRACT:
The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.

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Egly et al Journal of Chromatography vol. 243, pp. 301-306 (1982).
M. Egly et al., “Separation of Single-Stranded From Double Stranded Nucleic Acids Using Acri avin-Agarose Chromatography”, Journal of Chromatography, 243, (1982), pp. 301-306.

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