Prolonged release microparticle preparation and production of th

Details Prolonged release microparticle preparation and production of th Prolonged release microparticle preparation and production of th

1995-05-31

1997-04-22

Nutter, Nathan M.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 46, B01J 1304, B01J 1322

Patent

active

056226578

ABSTRACT:
A novel microparticle preparation comprising microparticles of a polymer which contain a drug and are coated with a film of an agent for preventing aggregation of the microparticles is disclosed. The preparation is produced by spraying a solution of a polymer containing a drug and an aqueous solution of an agent for preventing aggregation of the microparticles separately from different nozzles and contacting them with each other in a spray dryer.

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Bodmeier et al., "Preparation Of Biodegradable Poly(.+-.)lactide Moroparticles Using a Spray-Drying Technique", J. Pharm. Pharmacol., 1988, vol. 40, pp. 764-767.

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