Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-05-03
2005-05-03
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S032000, C536S017200, C536S017300, C536S017400, C536S017500, C536S017600, C536S017700, C536S017800, C536S017900, C536S018100, C548S146000, C548S215000, C548S300100, C548S400000
Reexamination Certificate
active
06887854
ABSTRACT:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
REFERENCES:
patent: 5627027 (1997-05-01), Waggoner
patent: 5877310 (1999-03-01), Reddington et al.
patent: 6027709 (2000-02-01), Little et al.
patent: 6083485 (2000-07-01), Licha et al.
patent: 6114350 (2000-09-01), Randall et al.
patent: 6180086 (2001-01-01), Achilefu et al.
patent: 6183726 (2001-02-01), Achilefu et al.
patent: 6190641 (2001-02-01), Achilefu et al.
patent: 6258340 (2001-07-01), Licha et al.
patent: 6264919 (2001-07-01), Achilefu et al.
Christopher C. Baker, M.D.,Epidemiology of Trauma Deaths, Amer. Jour. of Surg., vol. 140, 1980, pp. 144-150.
John Baldas et al.,Preparation, HPLC Studies and Biological Behaviour of99mTc- and99mTcN-radiopharmaceuticals Based on Quinoline Type Ligands, Nucl. Med. Biol., vol. 19, No. 4, 1992 pp. 491-496.
Frank B. Cerra, M.D.,Multiple Organ Failure Syndrome, New Horizons: Multiple Organ Failure, Society of Critical Care Medicine, 1989, pp. 1-24.
Peter L. Choyke et al.,Hydrated clearance of gadolinium-DTPA as a measurement of glomerular filtration rate, Kidney International, vol. 41, 1992, pp. 1595-1598.
Cdr. P.D. Doolan, MC, USN et al.,A Clinical Appraisal of the Plasma Concentration and Endogenous Clearance of Creatinine, AMer. Jour. of Med., vol. 32, 1962, pp. 65-79.
Richard B. Dorshow et al.,Monitoring physiological function by detection of exogenous fluorescent contrast agents, Optical Diagnostics of Biological Fluids IV, A. Priezzhev and T. Asakura, Eds., Procedings of SPIE 1999, vol. 3599.
Richard B. Dorshow et al.,Noninvasive Fluorescence Detection of Hepatic and Renal Function, Journal of Biomedical Optics, vol. 3, No. 3, 1998, pp. 340-345.
James H. Flanagan, Jr. et al.,Near-Infrared Heavy-Atom-Modified Fluorescent Dyes for Base-Calling in DNA-Sequencing Applications Using Temporal Discrimination, Anal. Chem., vol. 70, No. 13, 1998, pp. 2676-2684.
P. Guesry et al.,Measurement of glomerular filtration rate by fluorescent excitation of non-radioactive meglumine iothalamate, Clinical Nephrology, vol. 3, No. 4, 1975, pp. 134-138.
Hansen et al.,Synthesis of the Sulphonate and Phosphonate Derivatives of Mercaptoacetyltrigylcine, X-Ray Crystal Structure of Na4ReO (Mercaptoacetylglycylglycyl-Aminomethanesulphonate))-3H2O, Metal-Based Drugs, vol. 1, No. 1, 1993, 31-39.
John Bernard Henry, M.D.,Clinical Diagnosis and Management by Laboratory Methods, W.B. Saunders Company, 17th Ed., 1984, Pp. vil-1502.
Richard Lewis et al.,Comparative Evaluation of Urographic Contrast Media, Inulin, and99mTo-DTPA Clearance Methods for Determination of Glomerular Filtration Rate in Clinical Transplantation, Transplantation, vol. 48, no. 5, 1989, pp. 790-796.
S. Lundqvist et al.,Iohexol Clearance for Renal Function Measurement in Gynaecologic Cancer Patients, Acta Radiologica, vol. 37, 1996, pp. 582-586.
G. Muller et al. (ed.),Medical Optical Tomography, Functional Imaging and Monitoring, SPIE Optical Engineering Press, The International Society of Optical Engineering, Bellingham, WA 1993.
Roland Muller-Suur et al.,Glomerular Filtration and Tubular Secretion of MAG-3 in the Rat Kidney, The Journal of Nuclear Medicine, vol. 20, 1989, pp. 1986-1991.
Dennis L. Nosco et al.,Chemistry of technetium radiopharmaceuticals 1: Chemistry behind the development of technetium: 99m compounds to determine kidney function, Coordination Chemistry Reviews, vol. 184, 1999, pp. 91-123.
Carlos A. Rabito et al.,Renal Function in Patients at Risk of Contrast Material-induced Acute Renal Failure: Noninvasive, Real-Time Monitoring, Radiology, vol. 186, No. 3, 1993, pp. 851-854.
G. Regel, M.D. et al.,Treatment Results of Patients with Multiple Trauma: An Analysis of 3046 Cases Treated between 1972 and 1991 at a German Level 1 Trauma Center, The Journal of Trauma, vol. 38, No. 1, 1995, pp. 70-77.
G.A. Reynolds et al.,Stable Heptamethine Pyrulium Dyes That Absorb in the Infrared, J. Org. Chem., vol. 42, No. 5, 1977, pp. 885-888.
Francoise Roch-Ramel et al.,Renal excretion and tubular transport of organic anions and cations, Oxford University Press, N.Y., Handbook of Physiology, Sec. 8, Neurological Physiology, vol., II, E.E. Windhager, Ed., 1992, pp. 2189-2262.
Morgan Schtell et al.,FITC-insulin as a kidney tubule marker in the rat, Acta Physiol. Scand., vol. 119, 1983, pp. 313-316.
P.L., Southwick et al.,“One Pot” Fischer Synthesis of(2, 3, 3-Trimethyl-3-H-Indot-5-yl)-Acetic Acid, Derivatives as Intermediates for Fluorescent Biolabels, Org. Prep. Proced. Int. Briefs, vol. 20, No. 3, 1988, 279-284.
Carl E. Speicher, M.D.,The Right Test, A Physician's Guide to Laboratory Medicine, W.B. Saunders Company, Harcourt, Brace, Jovanovich, Inc., 1990, pp. v-174.
W. Newton Tauxe,Tubular Function, Nuclear Medicine in Clinical Urology and Nephrology, Appleton-Century-Crofts, Prentice-Hall, Inc., 1985, p. 77-105.
Nicholas L. Tilney, M.D.,Acute Renal Failure in Surgical Patients, Causes, Clinical Patterns, and Care, Surgical Clinics of North America, vol. 63, No. 2, 1963, pp. 357-377.
Michael F. Tweedle, Ph.D. et al.,A Noninvasive Method for Monitoring Renal Status at Bedside, Investigative Radiology, vol. 32, No. 12, 1997, pp. 802-805.
Bruce E. VanZae, M.D. et al.,Renal Injury Associated with Intravenous Pyelography in Nondiabetic and Diabetic Patients, Annals of Internal Medicine, vol. 89, 1978, pp. 51-54.
Achilefu Samuel
Bugai Joseph E.
Dorshow Richard B.
Jimenez Hermo N.
Rajagopalan Raghavan
Mallinckrodt Inc.
McIntosh III Traviss C.
Wilson James O.
Wood Herron & Evans L.L.P.
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