Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2005-07-12
2005-07-12
Afremova, Vera (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S366000, C435S383000, C435S404000
Reexamination Certificate
active
06916655
ABSTRACT:
A cultured skin and a grafting cultured skin sheet are provided, each of which is a cultured reconstructive skin with a high take rate using cells collectable from cells originated from tissue included in an umbilical cord such as tissue included in an umbilical cord originated from a human fetus. The grafting cultured skin stratified sheet is prepared by placing an epithelium sheet on the top surface of a cultured dermis. The cultured dermis includes as components a cultured skin containing cells originated from a tissue included in an umbilical cord, such as umbilical cells, more concretely, umbilical fibroblast cells, being separated and cultured, preferably in a collagen nonwoven fabric. On the other hand, the epithelium sheet is prepared by culturing and stratifying the umbilical cord epithelium cells.
REFERENCES:
patent: 4883487 (1989-11-01), Yoshizato et al.
patent: 5712163 (1998-01-01), Parenteau et al.
patent: 36 08 329 (1987-09-01), None
patent: 101 09 136 (2002-09-01), None
patent: 101 09 136 A 1 (2002-09-01), None
patent: 0 012 774 (1980-07-01), None
patent: 0 084 157 (1983-07-01), None
patent: 2 563 727 (1985-11-01), None
patent: 2 563 727 (1985-11-01), None
patent: 2 365 443 (2002-02-01), None
patent: 4-332561 (1992-11-01), None
patent: 5-184662 (1993-07-01), None
patent: 2000-125855 (2000-05-01), None
patent: 96/12510 (1996-05-01), None
patent: 00/30695 (2000-06-01), None
Pelletier et al. Epithelial cells primary cultures and fibroblasts long-term cultures from human umbilical cord ultrastructural and immunocytochemical characterization. C. R. Soc. Biol. 1986, 180, pp. 447-459.
Black, Annie F., et al.; “In vitroreconstruction of a human capillary-like network in a tissue-engineered skin equivalent”;The FASEB Journal; vol. 12, No. 13, pp. 1331-1340; Oct. 1998.
Black, A.F. et al.; “In vitroReconstruction of a Human Capillary-like Network in a Tissue-engineered Skin Equivalent”;The FASEB Journal; vol. 12, pp. 1331-1340; 1998.
Mizoguchi, M. et al.; “Reconstruction of a Human Skin Equivalent using Epithelial Cells Derived from Umbilical Cord”;The Journal of Investigative Dermatology; vol. 117, p. 422; 2001; abstract.
Mizoguchi, M. et al.; “Expression of Cytokeratins and Cornified Cell Envelope-Associated Proteins in Umbilical Cord Epithelium: a Comparative Study of the Umbilical Cord, Amniotic Epithelia and Fetal Skin”;The Journal of Investigative Dermatology; vol;. 115, pp. 133-134; 2000.
Gu, J. et al.; “Detection of Endothelin-like Immunoreactivity in Epithelium and Fibroblasts of the Human Umbilical Cord”;Tissue and Cell; vol. 23, pp. 437-444; 1991.
Takeuchi Masakatsu
Yasumoto Shigeru
Afremova Vera
Kubovcik & Kubovcik
Nipro Corporation
LandOfFree
Cultured skin and method of manufacturing the same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cultured skin and method of manufacturing the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cultured skin and method of manufacturing the same will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3387968