Nucleic acid and amino acid sequences of infectious salmon...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

Reexamination Certificate

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C424S186100, C424S204100, C514S002600, C514S04400A, C435S005000, C435S006120, C435S007100, C435S320100, C435S325000

Reexamination Certificate

active

06919083

ABSTRACT:
The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence which is derived from ISAV or synthetically prepared analogues thereof, or substantially homologous sequences. These nucleic acid sequences are transcripted and translated into peptide sequences which are incorporated into a vaccination strategy to induce an immune response to the surface antigens of ISAV and therefore ISAV itself. Therefore both the use of a vaccine against ISAV, and the incorporation of peptide sequences, is herein described.

REFERENCES:
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patent: WO 01/49712 (2001-01-01), None
patent: WO 01/66569 (2001-09-01), None
patent: WO/ 02/26784 (2002-04-01), None
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Krossoy B. et al.: “The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within theOrthomyxoviridae” Journal of Virology, (Mar. 1999) 73 (3) 2136-42, XP000986368.
Kibenge et al. “Antigenic VarIation Among Isolates of Infectios Salmon Anaemia Virus Correlates with Genetic Variation of the Viral Haemagglutinin Gene”, Journal of General Virology, vol. 82, pp. 2869-2879, (2001).
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Mjaaland et al. “Genomic Charcterization of the Virus Causing Infectious Salmon Anemia in Atlalntic Salmon (Salmo salarL.): an Orthomyxo-Like Virus in Teleost”, Journal of Virology, vol. 71, No. 10, pp7681-7686, (1997).
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