Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Patent
1991-06-20
1992-07-14
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
514467, A61K 3324, A61K 31335
Patent
active
051301458
ABSTRACT:
Anti-cancer platinum complexes such as cisplatin exhibit a synergistically higher level of anti-tumour activity when administered substantially simultaneously either with L-ascorbic acid, or with 5,6-O-benzylidene-L-ascorbic acid or deuterated forms thereof.
REFERENCES:
See-Lasley et al., Manual of Oncology & Jerapeutics, 1981, pp. 189-190.
Carter et al., Chemotherapy of Cancer, 2nd Ed. 1981, pp. 107-108.
Zaizen et al., J. Cancer Research Clin. Oncol. (1986) III, pp. 93-97.
Nechay et al., Cancer Treat. Rep., vol. 68, No. 9 Sep., 1984, pp. 1135-1141.
Borretzen Bernt
Dornish John M.
Larsen Rolf O.
Oftebro Reidar
Pettersen Erik O.
Goldberg Jerome D.
Norsk Hydro a.s.
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