Methods for in situ prepared calcium phosphate minerals

Surgery – Instruments – Orthopedic instrumentation

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423305, 423308, 423311, 4332281, 106 35, C01F 1102, A61K 633

Patent

active

051299054

ABSTRACT:
Calcium phosphate minerals are formed by using phosphoric acid source substantially free of uncombined water in conjunction with a calcium source, normally as any combination of carbonate, phosphate and hydroxide, and, as required, any additional base to neutralize the phosphoric acid. Protein may be optionally added. The resulting product is readily formed and then sets to a hard, stable, workable shaped object.

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patent: 4487749 (1984-12-01), Sherif et al.
patent: 4497075 (1985-02-01), Niwa et al.
patent: 4849193 (1989-07-01), Palmer et al.
patent: 4880610 (1989-11-01), Constantz
Lemaitre, Jacques et al., Silicates Industriels (1987) 9-10;141-146.

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