Asymmetric hydrogenation of beta- or gamma-ketoesters and beta-

Details Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- Asymmetric hydrogenation of beta- or gamma-ketoesters and beta-

1994-01-05

1996-04-16

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548482, 546216, 549346, 549356, 549429, 560115, 560151, 560179, 564186, 435 6, 540524, 540531, C07D31302, C07D20724, C07D21140, C07D22502, C07C22304

Patent

active

055084354

ABSTRACT:
.beta.- or .gamma.-Ketoesters and .beta.- or .gamma.-ketoamides are asymmetrically reduced with a Ru(II)-BINAP derived catalyst at about 40.degree. C. and about 50N/mm.sup.2 of hydrogen in the presence of a strong acid.

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