Method for disinfecting red blood cells

Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using disinfecting or sterilizing substance

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422 37, 424605, 424616, 424661, 424666, 424672, 435 2, 514694, 514731, 514739, A61K 3105, A61K 31055, A61K 31115, A61K 3318

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051853710

ABSTRACT:
A method to inactivate viruses or to disinfect blood products, for instance units of red blood cells, wherein a disinfectant or virus inactivating chemical is made isotonic or nearly isotonic, and wherein the red blood cells are exposed to isotonic disinfectant to inactivate any agent which may be present, for example HIV-1 virus which causes AIDS. The method may also be applied to plasma fractions and corneas.

REFERENCES:
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patent: Re31779 (1984-12-01), Alliger
patent: 3031378 (1962-04-01), Ishidate et al.
patent: 3100737 (1963-08-01), Auerswald et al.
patent: 4314997 (1982-02-01), Shanbrom
patent: 4481189 (1984-11-01), Prince
patent: 4632980 (1986-12-01), Zee et al.
patent: 4675159 (1987-06-01), Al-Sioufi
patent: 4833165 (1989-05-01), Louderback
Inactivation of Lymphadenopathy Associated Virus by Chemical Disinfectants, Spire et al., The Lancet, Oct. 20, 1984.
Inactivation of Human T-Cell Lymphotropic Retrovirus (HTLV-III) by LD, Sarin et al., The New England Journal of Medicine, Nov. 28, 1985.

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