Test kit containing labeled receptor and wash solution for deter

Details Test kit containing labeled receptor and wash solution for deter Test kit containing labeled receptor and wash solution for deter

1990-11-01

1993-02-09

Hill, Jr., Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Sample mechanical transport means in or for automated...

435 75, 435 792, 435311, 435962, 435975, 436510, 436518, 436531, 436808, 436814, 436818, G01N 3353, G01N 3358

Patent

active

051851288

ABSTRACT:
A test kit useful for the determination of an immunological ligand includes a labeled receptor for that ligand, a specific wash solution and a test device. The wash solution is buffered to a pH of from about 5 to about 9 and contains at least 0.01 weight percent of a compound having a dodecyl sulfate anion and an alkali metal or ammonium cation. One such compound is sodium dodecyl sulfate. The test device has several test wells, and in each well there is a microporous membrane. A receptor for the ligand of interest is immobilized in one test well. The kit is particularly useful for measuring human chorionic gonadotropin as an early indicator of pregnancy.

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patent: 5017474 (1991-05-01), McClune et al.
Odell et al., Clin. Chem., 32 (10), pp. 1873-1878 (1986).
Qualitiere et al., J. Immun. 119, pp. 1645-1651 (1977).

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