Measurement of bile pigments in serum or plasma

Details Measurement of bile pigments in serum or plasma Measurement of bile pigments in serum or plasma

1997-05-23

1999-08-17

Wallenhorst, Maureen M.

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-n

436164, 702 19, G01N 3300

Patent

active

059393270

ABSTRACT:
A method which provides a quick simple means of assessing plasma or serum specimen integrity with respect to bile pigments is described. Application of the method simultaneously screens serum or plasma specimens for elevated levels of bilirubin (BR) and biliverdin (BV) by providing a measure of these interferents known as the bilirubin-biliverdin index or BBI. The method involves determination of concentrations of BV in a plasma or serum specimen, based on the results of spectrophotometric determinations of absorbance or reflectance measurements conducted in the near infrared region, and thereby a determination of the BBI in respect of the specimen and on the basis of the resulting BBI a decision as to acceptance or rejection of the sample.

REFERENCES:
patent: 3477818 (1969-11-01), Fried et al.
patent: 4839279 (1989-06-01), Kosaka et al.
patent: 4985360 (1991-01-01), Takahashi
patent: 5262304 (1993-11-01), Taniguchi
patent: 5278073 (1994-01-01), Grandjean

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