Nucleic acid matrices

Details Nucleic acid matrices Nucleic acid matrices

1993-06-21

1996-01-16

Jones, W. Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 912, 435810, 436501, 536 221, 536 241, 536 242, 536 243, 536 2431, 536 2432, 536 2433, 536 253, 935 77, 935 78, C12Q 168, C07H 2100, C07H 2102, C07H 2104

Patent

active

054849047

ABSTRACT:
A novel class of reagents for assaying nucleic acid sequences comprise successive layers of polynucleotides of a specific structure, including a double-stranded waist and single-stranded, free arms at the molecule ends, formed by hybridization of the arms to adjacent molecule arms. The reagent is used to assay for specific nucleic acid sequences. The outer layer of polynucleotides are specific for the sequence to be assayed through their non-annealed, free, single-stranded arms. The reagents are useful in the assay of a wide variety oil nucleic acid sequences including those associated with pathogens such as pathogenic bacteria and virus.

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