Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from panax or acanthopanax
Reexamination Certificate
2001-03-09
2003-07-01
Tate, Christopher R. (Department: 1651)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from panax or acanthopanax
C424S725000, C424S757000, C424S773000
Reexamination Certificate
active
06586017
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to compositions comprising “Denhichi” (“
Panax pseudo
-
ginseng
”) and “Tochu” (“
Eucommiae ulmoides
(Eucommia Bark)”, and, if desired, comprising “Osei” (“
Polygonati Rhizoma
”) and/or gallic acid-containing herbal extracts and “Kanzo” (“Licorice root”) additionally and provides a method for its production.
The composition of the present invention can be used effectively not only for human healthcare and health promotion and improvement of nutritional state and immune system, but also for therapy or protection against hepatitis and infectious diseases, as conventional or alternative medicine and food supplements.
In addition, the composition of the present invention can be used as food supplements not only for protection against hypertension and diabetes mellitus of animals such as dogs, cats, pigs, cattle, horses and others, but also for healthcare and improvement of the nutritional state and immune system of these animals including birds and fish.
2. Description of the Related Art
Results of a nationwide survey indicate a marked increase in the number of individuals, who suffered from overweight, hypertension and diabetes mellitus, because of their environmental conditions, lack of exercise and high-calorie diets. Accordingly, ability for protection against hepatitis, infectious disease and immune disease will be markedly lowered.
These observations can be seen in the animal's environment. In fact, pet animals kept in a small area, e.g., in the rooms of a house, tend to suffer from disorders of nutritional state, hypertension, psychosomatic stress and overweight bodies with high fat mass.
On the other hand, increase of a patient's suffering with HBV and HCV are also serious problems to be solved.
In general, interferons have been used for therapy of patients suffering with HBV and HCV, although interferons had been known to have strong unfavorable side effects.
SUMMARY OF THE INVENTION
It is an object of this invention to provide food supplements and alternative medicines having an effect for significant improvements in symptoms such as high cholesterol, hypertension, diabetes mellitus and some cancers (in order to keep in healthy condition).
A further object is to provide alternative medicines which afford significant improvements in the symptoms of HBV and HCV, when compared with therapy with interferons.
The first objects of this invention have been attained by providing food supplements and the related products and alternative medicines comprising “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoides
”, and if required, comprising “
Polygonati Rhizoma
” and/or gallic acid-containing herbal extracts and “Licorice root (
Glycyrrhiza glabra
)”.
Still another object of this invention is to provide alternative medicine comprising “
Panax pseudo
-
ginseng”, “Eucommiae ulmoides
”, and if desired, comprising “
Polygonati Rhizoma
” and/or gallic acid-containing herbal extracts and “Licorice root”, which are effective for therapy in symptoms with various liver disorders.
Also provided herein are compositions comprising “
Panax pseudo
-
ginseng”, “Eucommiae ulmoides
”, gallic acid-containing herbal extracts and “Licorice root (
Glycyrrhiza glabra
)”, which are useful as food supplements for healthcare, alternative medicine for therapy of liver disorders, supplemental products, products for drink, animal foods and food compounds for animals, birds and fish.
Also, provided herein are compositions comprising “
Panax pseudo
-
ginseng”, “Eucommiae ulmoides”, “Polygonati Rhizoma
”, and if desired, comprising “Licorice root”.
The present invention provides a method for production of the above-mentioned composition which comprises obtaining condensed extracts of “Panax pseudo-
ginseng
” and “
Eucommiae ulmoides
” by condensing hot-water (60-100° C.) or alcoholic (room temperature to 100° C.) extracts of minced dry “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoises
”, and if desired, their pulverized product by heat drying; obtaining condensed extracts of gallic acid-containing herbal extracts by condensing hot-water (60-100° C.) or alcoholic (room temperature to 100° C.) extracts of minced dry gallic acid-containing herbal extracts and if desired their pulverized products by heat drying; and mixing and then drying extracts of pulverized products of “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoides
”, extracts of pulverized products of gallic acid-containing herbal extracts, and extracts or pulverized products of “Licorice root”.
The present invention provides a method for production of the above-mentioned composition which comprises obtaining condensed extracts of “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoides
” by condensing hot-water (60-100° C.) or alcoholic (room temperature to 100° C.) extracts of minced dry “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoides
”, and if desired, their pulverized product by heat drying; obtaining condensed extracts of “
Polygonati Rhizoma
” by condensing hot-water (60-100° C.) or alcoholic (room temperature to 100° C.) extracts of minced dry “
Polygonati Rhizoma
” and if desired their pulverized products by heat drying; and mixing and then drying extracts or pulverized products of “
Panax pseudo
-
ginseng
” and “
Eucommiae ulmoides
”, extracts or pulverized products of “
Polygonati Rhizoma
”, and extracts or pulverized products of “Licorice root”.
Alternative medicines, food supplements, products for drinking and healthcare food for humans and animals comprising the above compositions are effective for lowering blood sugar and cholesterol and for enhancing the immune system.
In addition, the composition of the present invention shows the effect of lowering the elevated GOT and GTP levels. Especially, oral administration of compositions containing “
Polygonati Rhizoma
” and/or gallic acid-containing herbal extracts resulted in the reduction of elevated &agr;-Fetoprotein and albumin in humans, suggesting that compositions of the present invention may be effective for prevention or reduction of the symptoms connected with high blood cholesterol, hypertension and diabetes mellitus, and also useful for prevention of chronic hepatitis. Although “
Polygonati Rhizoma
” and/or gallic acid-containing herbal extracts themselves have been known to be difficult to absorb into human or animal bodies, compositions of this invention comprising “
Polygonati Rhizoma
” and/or gallic acid-containing herbal extracts can be readily absorbed into human and animal bodies.
REFERENCES:
patent: 4446130 (1984-05-01), Hachiya et al.
patent: 5589182 (1996-12-01), Tashiro et al.
patent: 6123946 (2000-09-01), Wei
patent: 1096217 (1994-12-01), None
patent: 1084754 (1996-04-01), None
patent: 1144106 (1997-05-01), None
patent: 08 073369 (1996-03-01), None
patent: 09 023851 (1997-01-01), None
patent: 2099986 (1997-12-01), None
patent: WO 97/33549 (1997-09-01), None
Johnson, T. CRC Ethnobotany Desk Reference. 1999. CRC Press, NY, NY, p. 651.*
Matsushima, “Rinsho & Kenkyu”, vol. 56(10), 345(3461) (1979).
Y. Ishii, Japan J. Pharaco., 120 71 (1971).
“Preventive effects of the extract of Du-Zhong (Tochu) leaf and Ginseng root on acute toxicity of chlorpyrifos,” Japanese Journal of Toxicology and Environmental Health, 1997, vol. 43, No. 2, pp. 92-100 (abstract).
Mechanism of the protective effects of sumac gall extract and gallic acid on the progression of CC14-induced acute liver injury in rats, American Journal of Chinese Medicine 1998, vol. 26, No. 3-4, pp. 333-341 (abstract).
Computer JPAB Abstract JP408191668 Kanamaru “Pet Food” Jul. 30, 1996.
Computer Derwent Abstract 1997-539684 Taisho Pharm Co., Ltd JP 09227394 “Oral Composition with Tranquilliser Effect—Contains Rhizomes ofEleuterococcus senticocus, Bark ofEucommiae ulmoidesOliv.” Sep. 2, 1997.
Computer Toxline Abstract 1995: 105742 Kosuge et al J. Pharm Soc. JAP (1981) Vol. 101 No. 6 pp 501-503.
Computer Napralert Abstract 94: 3763 Yang Zhejiang-Zhongyi Zazhi (1989) 24 (9) 397-398.
Computer Derwent Abstract JP 09023851 Jan. 28, 199
Sha Shinhan
Yanaihara Noboru
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Sha Shinhan
Tate Christopher R.
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