Sustained release microcapsule for water soluble drug

Details Sustained release microcapsule for water soluble drug Sustained release microcapsule for water soluble drug

1991-08-15

1993-12-21

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

264 41, 264 46, 424452, 424455, 424462, 424499, 424501, 42840221, 42840222, 514800, 514963, A61K 952, A61K 966, B01J 1308, B01J 1312

Patent

active

052719456

ABSTRACT:
Sustained release microcapsules including a water soluble drug and an organic basic substance as a drug retaining substance of this invention not only have a high rate of incorporation (trapping rate), but also show little initial release so that they can be administered safely and bring about persistent, stable sustained release.

REFERENCES:
patent: 4205060 (1980-05-01), Monsimer et al.
patent: 4479911 (1984-10-01), Fong
patent: 4483807 (1984-11-01), Asano et al.
patent: 4671954 (1987-06-01), Goldberg et al.
patent: 4728512 (1988-03-01), Mehta et al.
patent: 4917893 (1990-04-01), Okada et al.
patent: 4954298 (1990-09-01), Yamamoto et al.
"Preparation of Microcapsule", Patent Abstracts of Japan, vol. 12, No. 297 Aug. 12, 1988.

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