Method of and imaging ultrasound system for determining the...

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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C128S916000

Reexamination Certificate

active

06587709

ABSTRACT:

The invention relates to a method of determining the position of a catheter in an ultrasound image acquired by means of an ultrasound transducer. The invention also relates to an imaging ultrasound system that is intended for imaging a region of a body and is suitable for carrying out such a method.
The determination of the position, or localization, of a catheter introduced into the vascular system of a patient is performed preferably by means of X-ray fluoroscopy in conformity with the present state of the art. This is applicable notably to examinations and therapeutic interventions in the cardiovascular field. Even though X-ray fluoroscopy is comparatively simple in respect of application, it has the drawback that the patient and the medical staff are exposed to radiation.
In order to avoid such a radiation load it is known to track and guide a catheter by way of an imaging ultrasound system. Systems of this kind offer the additional advantage of soft tissue contrast. It is particularly desirable to use 3D ultrasound scanners that acquire image information in real time from a three-dimensional body volume by means of ultrasound transducer units that are arranged in a flat two-dimensional array (2D). In achieving an appropriate and suitably understandable representation of the three-dimensional information, however, a further problem is encountered. When a two-dimensional image plane is selected from the scanned volume so as to be displayed, it usually does not contain the catheter which, therefore, cannot be guided by way of such an image section. Movements of the body that are due to, for example, respiration or cardiac action complicate matters further. The ultrasound source used, therefore, usually has to be displaced and re-oriented by hand and continuously so as to track the position of interest of the catheter.
U.S. Pat. No. 4,706,681 discloses a method of determining the position of the tip of a stimulation electrode that is arranged in the heart; according to this method an ultrasound receiver is integrated in said tip. This receiver generates an electric signal when it is struck by the fan-shaped two-dimensional scan beam of a 1D ultrasound transducer. This signal is fed out via the electrode wire and can be detected by an evaluation unit. The occurrence of this signal thus provides an indication that the tip of the electrode is situated exactly in the radiation range of the ultrasound transducer. This makes it possible to distinguish the tip of the electrode from an arbitrary section through the electrode wire in the ultrasound image. However, the position of the electrode cannot be determined beyond the image information of the ultrasound transducer.
WO 96/25881 discloses a method of tracking the position of an instrument inside the body of a patient; according to this method the region of operation of the instrument is monitored and displayed by means of an imaging ultrasound system, the position of the instrument being determined at the same time by way of a magnetic positioning system. In the case of a rigid instrument the position of its end that is situated outside the body can thus be determined and the position of the tip that is situated inside the body can be deduced therefrom. The information of the positioning system and of the ultrasound system is then combined in the reproduction of the region of operation in an image processing system.
Furthermore, U.S. Pat. No. 5,954,649 and WO 00/07501 disclose methods in which one or more reference catheters with ultrasound transmitters are introduced into the body and a catheter that is to be monitored and is provided with at least one ultrasound receiver is positioned in the vicinity of the region of operation. This arrangement enables determination of the position of the catheter relative to the reference catheters by measurement of the transit time of ultrasound signals. However, it is a drawback that additional reference catheters must be used and that the position is determined only with respect to the reference catheters whose location itself is not known exactly.
Considering the foregoing it was an object of the present invention to provide a method of and a system for the imaging of a catheter within the body of a patient that are less of a burden to the patient and at the same time provide more information for the user.
This object is achieved by means of a method as disclosed in the characterizing part of claim 1 and by means of an imaging system as disclosed in the characterizing part of claim 8. Further advantageous embodiments are disclosed in the dependent claims.
The method serves to determine the position of a catheter in an ultrasound image acquired by means of an ultrasound transducer; in this method the ultrasound transducer is provided in known manner with at least one transmission element for the transmission of ultrasound scan signals and at least one receiving element for the reception of echoes of the scan signals that emanate from the body. The transmission and receiving element (elements) may also be one and the same element. Furthermore, in conformity with the method the catheter is provided with at least one ultrasound receiver that detects the reception of ultrasound scan signals that were emitted by the ultrasound transducer. The transit time of the ultrasound scan signals from the transmission element of the ultrasound transducer to the receiver in the catheter is then measured and the distance between the ultrasound transducer or the receiving element and the receiver on the catheter is determined from the transit time thus measured.
The described method offers the advantage that it enables more accurate determination of the position of the catheter relative to the ultrasound transducer that is usually situated outside the body, because the respective distance between these two elements is determined in conformity with this method. The information thus obtained can then be used for more exact localization of the catheter of interest in an ultrasound image.
Preferably, the ultrasound transducer is configured in such a manner that it acquires a three-dimensional ultrasound image. Such a transducer includes a plurality of transmission units, so that the distance can be determined between the ultrasound receiver or the ultrasound receivers on the catheter and each of the transmission units. This enables determination of the exact position in space of each ultrasound receiver on the catheter.
When an ultrasound transducer that acquires a three-dimensional image is used, the proposed method enables, on the basis of the position of the ultrasound receiver on the catheter that can thus be detected, a plane to be selected for display from the three-dimensional ultrasound image, that is, in dependence on the position of said ultrasound receiver. This plane may notably be a plane that contains the ultrasound receiver and hence also the catheter. Consequently, it is no longer necessary to displace the ultrasound transducer or the plane reproduced in the three-dimensional ultrasound image in conformity with the catheter by hand; this plane can now be found automatically by means of the position of the ultrasound receiver on the catheter.
The catheter preferably includes at least three ultrasound receivers so that the position in space of three different points of the catheter can be determined. These three points then define a plane wherethrough the catheter extends. When this plane is selected for display from a three-dimensional ultrasound image, it is ensured that it will contain the catheter for a prolonged period of time. For the exceptional case where all ultrasound receivers on the catheter are oriented along one line and hence do not define an unambiguous plane, an arbitrary one of said planes can be selected for display; all three of said planes then contain an ultrasound receiver.
For the display of the acquired ultrasound image, for example, on a monitor, the position of the receiver or the receivers on the catheter that is known from the transit time measurements is preferably hig

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