Aurothiosteroids

Details Aurothiosteroids Aurothiosteroids

1980-03-10

1981-05-05

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039745, 2603971, 2603975, 424238, 424243, C07J 500

Patent

active

042658233

ABSTRACT:
A novel class of gold-steroid compounds are produced by addition of aurothio substituents at various positions in steroids, particularly the 3-keto androstane, estrane and pregnane series unsaturated in the A ring. They possess potent anti-inflammatory properties and manifest unique therapeutic effects heretofore unavailable through conventional therapy.

REFERENCES:
patent: 3944576 (1976-03-01), Van den Broek et al.
patent: 4093721 (1978-06-01), Phillipps et al.
Oliveto et al., "JACS", (1958), p. 4431.

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