Pure crystalline methyl 2-acryloylamino-2-methoxy acetate and a

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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C07C10366

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active

049609238

ABSTRACT:
The process for preparing a novel product, pure crystalline methyl 2-acryloylamino-2-methoxyacetate, involves reacting pure crystalline, anhydrous acrylamido-glycolic acid in an anhydrous medium with methanol in the presence of hydrogen chloride. This is subsequently neutralized with an alkali metal bicarbonate, and then the mineral salts are filtered off. Finally, pure crystalline methyl 2-acryloylamino-2-methoxyacetate is obtained by taking up the concentrated reaction medium in 1,1,1-trichloroethane under vacuum.

REFERENCES:
patent: 4443623 (1984-04-01), Photis
patent: 4760168 (1988-07-01), Schirmann

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