Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1976-01-16
1978-01-03
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
23230B, 23253TP, 424 11, 424 13, 424 78, 424 87, 424 92, C12K 104, G01N 3100, G01N 3102, G01N 3106
Patent
active
040667448
ABSTRACT:
Disclosed are a reagent and test slide used for serological detection of gonorrheal antibodies in human blood serum or synovial fluid. The reagent comprises latex particles having absorbed on their surfaces an inert protein, such as bovine serum albumin and a heat labile antigen derived from Neisseria gonorrhoeae bacteria exhibiting T.sub.1 colonial morphology. The reagent may be employed by several forms, for example, as a liquid suspension of the latex particles, or in the form of a dried deposit of the latex particles. Regardless of the form employed, the reagent is particularly useful as a routine screening test in hospitals and prenatal clinics to detect gonococcal infection in women and also in cases of complicated gonorrhea, e.g., gonorrheal arthritis where infection is not conveniently detectable by present means. The test slide may have dried thereon an absorbing antigen for heterophile antibodies. If desired, diagnosis made by the test of the invention can be subsequently confirmed by conventional more expensive and time consuming means, if this is thought to be desirable.
REFERENCES:
patent: 3551555 (1970-12-01), Schuurs
patent: 3770383 (1973-11-01), Price
patent: 3828103 (1974-08-01), Fujita
Reising, Applied Microbiology, vol. 21, May, 1971, pp. 852-853.
Cohen, J. of Bact., vol. 94, July 1967, p. 141-148.
Price Richard T.
Prodell Rita C.
Akzona Incorporated
Fagelson A. P.
Falk Robert H.
Meyers Albert T.
Wendel Charles A.
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