Polysaccharide containing phosphorylcholine group and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S053000, C536S055300

Reexamination Certificate

active

07348424

ABSTRACT:
The present invention is a method for manufacturing a phosphorylcholine group-containing polysaccharide wherein the aldehyde derivative-containing compound obtained by the oxidative ring-opening reaction of glycerophosphorylcholine is added to a polysaccharide containing amino groups as well as a new polysaccharide having phosphorylcholine groups obtained from this manufacturing method.The object of the present invention is to provide a phosphorylcholine group-containing polysaccharide that is superior in biocompatibility and moisture retention, and is useful as a polymer material for medical use, as well as a simple method of manufacturing it.The polysaccharide of the present invention is utilized, for example, in artificial organs, biomembranes, coating agents for medical tools, drug delivery, and in cosmetics.

REFERENCES:
patent: 0 580 871 (1993-12-01), None
patent: 10237102 (1998-09-01), None
Ishihara K: “Novel Polymeric Materials For Obtaining Blood-compatible Surfaces”, Trends In Polymer Science, Elsevier Science Publishers B. V. Amsterdam, NL, vol. 5, No. 12, Dec. 1997, pp. 401-407, XP004098788.

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