Nucleic acids encoding fibroblast growth factor...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S070100, C435S325000, C536S023100

Reexamination Certificate

active

07348162

ABSTRACT:
The present invention provides Fibroblast Growth Factor Receptor-Like (FGFR-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing FGFR-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with FGFR-L polypeptides.

REFERENCES:
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patent: WO 99/63088 (1999-12-01), None
patent: WO 00/24756 (2000-05-01), None
patent: WO 00/58463 (2000-10-01), None
Ngo et al., 1994, Computational Complexity, Protein Structure prediction, and the Levinthal Paradox, The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495.
Wells, Aditivity of Mutational Effects in Proteins, 1990, Biochemistry, vol. 26, No. 37, pp. 8509-8517.
Wiedemann et al., “Characterization of a Novel Protein (FGFR1) from Human Carilage Related to FGF Receptors.”Genomics, 2000, 69:275-279.
Wiedemann et al., “The Mouse Fgfr;1 Gene Coding for a Novel FGF Receptor-Like Protein,”Biochemica et Biophysica Acta, 2001, 1520:247-250.
Sleeman et al., “Identification of a New Fibroblast Growth Factor Receptor, FGFR5,”Gene, 2001, 271:171-182.
GENEBANK Acc. No. AI 245701.
Kim et al., A Novel Fibroblast Growth Factor Receptor-5 Preferentially Expressed in the Pancreas., Biochim. Biophys. Acta, 2001 1518:152-156.

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