Peptide inhibitor of TGF-β growth factors

Details Peptide inhibitor of TGF-β growth factors Peptide inhibitor of TGF-β growth factors

2008-07-22

2008-07-22

Romeo, David S (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S350000

Reexamination Certificate

active

07402566

ABSTRACT:
A potent peptide inhibitor (SuperSog) of TGF-β family growth factor signaling, peptide variants thereof and nucleotide coding sequences therefore are provided by the invention. The Super-Sog peptide comprises a fragment of theDrosophiliashort gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.

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