Methods for the treatment and amelioration of atopic dermatitis

Details Methods for the treatment and amelioration of atopic dermatitis Methods for the treatment and amelioration of atopic dermatitis

2011-08-16

2011-08-16

Spivack, Phyllis G. (Department: 1629)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

C514S315000

Reexamination Certificate

active

07998945

ABSTRACT:
The present invention relates to a method for the treatment and/or amelioration of atopic dermatitis, the method including the administration of a pharmaceutically active dose of a compound selected from miltefosine, edelfosine, perifosine and ilmofosine to a subject in need of such a treatment and/or amelioration.

REFERENCES:
patent: 5703063 (1997-12-01), Chasalow
patent: WO 2006/002422 (2006-01-01), None
Uenishi et al., Journal of Dermatology (Feb. 2003), 30(2), pp. 91-97 (abstract).
International Search Report for PCT International Application PCT/EP2006/012322, mailed Apr. 11, 2007 (4 pgs.).
Grosman N., “Effect of the Anti-Neoplastic Agents Edelfosine (ET-18-OCH3), ILMOFOSINE (BM 41.440) and the Hexadecylphosphocholine Analoges D-20133 and D-21266 on Histamine Release from Isolated Rat Mast Cells”,Immunopharmacology, vol. 44, No. 3, 1999, pp. 211-221. (XP008061676).
Mazer et al., “Dose-Dependent Agonist and Antagonist Effects of the Platelet-Activating Factor Analogue 1-Palmitoyl-2-Acetoyl-Sn-Gylcero-3-Phosphocholine on B Lymphocytes”Journal of Allergy and Clinical Immunology, vol. 102, No. 2, Aug. 1998, pp. 231-237. (XP005687525).

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