Production method of 5′-acyloxynucleoside compound

Details Production method of 5′-acyloxynucleoside compound Production method of 5′-acyloxynucleoside compound

2008-03-18

2008-03-18

Crane, L. E. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S027210, C536S028400

Reexamination Certificate

active

07345164

ABSTRACT:
A production method for conveniently producing a 5′-acyloxynucleoside compound shown by the formula [A] in a good yield while suppressing formation of by-products, including subjecting a 2′,3′,5′-triacyloxynucleoside compound represented by the formula [I] to selective deacylation in an alcohol represented by the formula [II] using a base selected from the group consisting of alkali metal hydroxide, alkali metal alkoxide and alkali metal carbonate:wherein each symbol in the formula is as defined in the specification.

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