Preparation of thiazoles

Details Preparation of thiazoles Preparation of thiazoles

2008-01-29

2008-01-29

Anderson, Rebecca (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C548S165000, C548S189000, C548S182000

Reexamination Certificate

active

07323564

ABSTRACT:
The present invention is directed to a process for preparing a compound having the formula:wherein R is a range of organic groups and X is a leaving group. The process may include reacting a compound of the formulawith a water-removing reagent. Also, when X is a halogen, the process may include reacting a compound of the formulawith a halogenating agent or a sulfonylating agent. Alternatively, when X is a halogen, the process may be carried out by reacting a compound of the formula IVwhere R2and R3are defined organic groups with a compound of the formula halogen-C(—O)—O—C1 -C8alkyl, halogen-C(—O)—O-aryl or halogen-C(—O)—O-benzyl.

REFERENCES:
patent: 5461167 (1995-10-01), Schiokawa et al.
patent: 192060 (1986-08-01), None
patent: 462573 (1991-12-01), None
patent: 9720829 (1997-06-01), None

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