3-substituted 6,7-dihydroxytetrahydroisoquinoline...

Details 3-substituted 6,7-dihydroxytetrahydroisoquinoline... 3-substituted 6,7-dihydroxytetrahydroisoquinoline...

2008-05-13

2008-05-13

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S146000

Reexamination Certificate

active

07371762

ABSTRACT:
The invention relates to novel tetrahydroisoquinoline derivatives of general formula I and theirs use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and their use as anti-infectives, wherein R1, R2and R3are as defined in claim 1.

REFERENCES:
patent: 5124337 (1992-06-01), Dugar et al.
patent: 8207825 (1983-06-01), None
patent: 2662940 (1991-12-01), None
patent: 1 475 913 (1977-06-01), None
Spangler et al., J. Org. Chem., vol. 39, pp. 1368-1374 (1974).
Vicario et al., J. Org. Chem., vol. 64, pp. 4610-4616 (1999).
Dominguez et al., Tetrahedron, vol. 44, pp. 203-208 (1988).
Yokoyama et al., J. Org. Chem., vol. 64, pp. 611-617 (1999).
Kim et al., Bioorganic & Medicinal Chemistry Letters 9, pp. 85-90 (1999).
Cox et al., Chemical Reviews, vol. 95, pp. 1797-1842 (1995).
O'Reilly et al., “Optically Pure (S)-6,7-Dimethoxy-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid and Asymmetric Hydrogenation Studies Related to Its Preparation”, Papers, pp. 550-556, Occidental Chemical Corporation, Technology Center, 2801 Long Road, Grand Island, NY 14072, U.S.A. (Jul. 1990).
Cope et al., “The Rearrangement of Allyl Groups in Three-carbon Systems. VI. Benzene and Phenanthrene Derivatives”, Departments of Chemistry of Bryn Mawr College and The Massachusetts Institute of Technology, U.S.A. vol. 78, pp. 2547-2551 (Jun. 5, 1956).
Organic Syntheses, Collective vol. 2, pp. 55-56 (Sixth Printing, Oct. 1950).
Valenta, Vladimir et al.; “Alpha-(4-TOLYL) Dopamine Derivatives”; Collection of Czechoslovak Chemical Communications, Academic Press, London, Great Britain, vol. 48, No. 5, 1983, pp. 1447-1463.

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