Thiazolylacetamido cephalosporin type compounds

Details Thiazolylacetamido cephalosporin type compounds Thiazolylacetamido cephalosporin type compounds

1975-12-19

1978-07-04

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 21, 544 27, C07D50136, A61K 31545

Patent

active

040988880

ABSTRACT:
Novel cephem compounds of the formula; ##STR1## wherein R.sup.1 represents amino or hydroxyl group which may be protected, R.sup.2 represents amino or hydroxyl group or a group convertible into these groups, R.sup.3 represents hydrogen or methoxy group or a group convertible into methoxy group, R.sup.4 represents hydrogen or a residue of a nucleophilic compound and R.sup.8 represents hydrogen or a halogen, or a pharmaceutically acceptable salt or ester thereof, have strong antibiotic properties against a wide variety of microorganisms including gram-positive bacteria as well as gram-negative ones, especially by oral administration and can be used as therapeutic agent for various bacterial infections of animals including human beings.

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patent: 3966717 (1976-06-01), Cook et al.
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patent: 4024134 (1977-05-01), Gregson et al.
patent: 4024137 (1977-05-01), Cook et al.
patent: 4032521 (1977-06-01), Christensen et al.
patent: 4039536 (1977-08-01), Takano et al.
patent: 4041029 (1977-08-01), Firestone et al.

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