Predicting mortality and detecting severe disease

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C436S516000, C436S518000

Reexamination Certificate

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07998683

ABSTRACT:
Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease.

REFERENCES:
patent: 5786163 (1998-07-01), Hall
patent: 6040147 (2000-03-01), Ridker et al.
patent: 6210976 (2001-04-01), Sabbadini et al.
patent: 6288218 (2001-09-01), Levinson
patent: 6323334 (2001-11-01), Kingsbury et al.
patent: 6905827 (2005-06-01), Wohlgemuth et al.
patent: 7087396 (2006-08-01), Tominaga et al.
patent: 7432060 (2008-10-01), Lee
patent: 2003/0124624 (2003-07-01), Tominaga et al.
patent: 2003/0228570 (2003-12-01), Yat Wah Tom et al.
patent: 2004/0048286 (2004-03-01), Lee
patent: 2004/0133079 (2004-07-01), Mazar et al.
patent: 2005/0130136 (2005-06-01), Lee
patent: 2005/0203046 (2005-09-01), Schmitz et al.
patent: 2005/0250156 (2005-11-01), Shebuski et al.
patent: 2005/0272054 (2005-12-01), Cargill et al.
patent: 2006/0216755 (2006-09-01), Lee
patent: 2007/0042978 (2007-02-01), Girard et al.
patent: 2007/0248981 (2007-10-01), Snider et al.
patent: 2008/0003199 (2008-01-01), Lee
patent: 2009/0192078 (2009-07-01), Lee
patent: 00/35473 (2000-06-01), None
patent: 00/73498 (2000-12-01), None
patent: 01/70817 (2001-09-01), None
patent: 02/38794 (2002-05-01), None
patent: 2004/056868 (2004-07-01), None
patent: WO03094856 (2005-03-01), None
Anwaruddin et al., “Renal function, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement: results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) Study,” J. Am. Coll. Cardiol., 47(1):91-97 (2006).
Baekkevold et al., “Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules,” Am. J. Path., 163(1):69-79 (2003).
Baggish et al., “A validated clinical and biochemical score for the diagnosis of acute heart failure: The ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) Acute Heart Failure Score,” Am. Heart J. 151:48-54 (2006).
Brint et al., “ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance,” Nat. Immunol., 5(4):373-379 (2004).
Bruneau, “Selective changes in natriuretic peptide and early response gene expression in isolated rat atria following stimulation by stretch or endothelin-1,” Cardiovasc. Res., 28(10):1519-1525 (1994).
Brunner et al., “Increased levels of soluble ST2 protein and IgG1 production in patients with sepsis and trauma,” Intensive Care Med., 30(7):1468-1473 (2004).
Dhalla et al., “Measurement of adrenolutin as an oxidation product of catecholamines in plasma,” Mol. Cell. Biochem., 87:85-92 (1989).
Januzzi et al., “Natriuretic peptide testing for the evaluation of critically ill patients with shock in the intensive care unit: a prospective cohort study,” Crit. Care, 10(1):R37 (2006).
Januzzi et al., “NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled analysis of 1256 patients: the International Collaborative of NT-proBNP Study,” Eur. Heart J., 27(3):330-337 (2006).
Januzzi et al., “The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study,” Am. J. Cardiol., 95(8):948-954 (2005).
Januzzi et al., “Utility of amino-terminal pro-brain natriuretic Peptide testing for prediction of 1-year mortality in patients with dyspnea treated in the emergency department,” Arch. Intern. Med., 166(3):315-320 (2006).
Kieser et al., “Identification of the primary growth response gene, ST2/T1, as a gene whose expression is differentially regulated by different protein kinase C isozymes,” FEBS Lett., 372(2-3):189-193 (1995).
Knudsen et al., “Predictors of elevated B-type natriuretic peptide concentrations in dyspneic patients without heart failure: an analysis from the breathing not properly multinational study,” Ann. Emerg. Med., 45(6):573-580 (2005).
Krauser et al., “Effect of body mass index on natriuretic peptide levels in patients with acute congestive heart failure: a ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) substudy,” Am. Heart J., 149(4):744-750 (2005).
Kumar et al., “ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1,” J. Biol. Chem., 270(46):27905-27913 (1995).
Kuroiwa et al., “Construction of ELISA system to quantify human ST2 protein in sera of patients. Hybridoma,” 19(2):151-159 (2000).
Lohning et al., “T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function,” Proc. Natl. Acad. Sci. U.S.A., 95(12):6930-6935 (1998).
Maisel et al., “Bedside B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure With Reduced or Preserved Ejection Fraction,” J. Am. Coll. Cardiol., 41:2010—7i (2003).
Maisel et al., “Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure,” N. Engl. J. Med., 347(3):161-167 (2002).
Maisel et al., “Primary results of the Rapid Emergency Department Heart Failure Outpatient Trial (REDHOT). A multicenter study of B-type natriuretic peptide levels, emergency department decision making, and outcomes in patients presenting with shortness of breath,” J. Am. Coll. Cardiol., 44(6):1328-1333 (2004).
McCord et al., “Relationship between obesity and B-type natriuretic peptide levels,” Arch. Intern. Med., 164(20):2247-2252 (2004).
McCullough et al., “B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study,” Am. J. Kidney Dis., 41(3):571-579 (2003).
Moe et al., “Neurohormonal activation in severe heart failure: relations to patient death and the effect of treatment with flosequinan,” Am. Heart. J., 139:587-95 (2000).
Oshikawa et al., “Acute eosinophilic pneumonia with increased soluble ST2 in serum and bronchoalveolar lavage fluid,” Respir. Med., 95(6):532-533 (2001).
Oshikawa et al., “Expression and function of the ST2 gene in a murine model of allergic airway inflammation,” Clin. Exp. Allergy, 32(10):1520-1526 (2002).
Oshikawa et al., “Expression of ST2 in helper T lymphocytes of malignant pleural effusions,” Am. J. Respir. Crit. Care Med., 165(7):1005-1009 (2002).
Oshikawa et al., “ST2 protein induced by inflammatory stimuli can modulate acute lung inflammation,” Biochem. Biophys. Res. Commun., 299(1):18-24 (2002).
Oshikawa et al., “Elevated soluble ST2 Protein Levels in Sera of Patients with Asthma with an Acute Exacerbation,” Am. J. Respir. Crit. Care Med. 164:277-281 (2001).
Sabatine et al., “Multimarker approach to risk stratification in non-ST elevation acute coronary syndromes: simultaneous assessment of troponin I, C-reactive protein, and B-type natriuretic peptide,” Circulation, 105(15):1760-1763 (2002).
Schmitz et al., “IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines,” Immunity, 23(5):479-490 (2005).
Shimizu et al., “Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis,” Hum. Mol. Genet., 14(19):2919-2927 (2005).
Shimpo et al., “Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction” Circulation, 109(18):2186-2190 (2004).
Strunk et al., “Impact of the history of congestive heart failure on the utility of B-type natriuretic peptide in the emergency diagnosis of heart failure: resu

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