Organic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S218000

Reexamination Certificate

active

07994203

ABSTRACT:
There are described pyrazolo[5.1-b]oxazole derivatives useful as corticotropin releasing factor (CRF1) receptor antagonists.

REFERENCES:
patent: 2002/0183375 (2002-12-01), Dubowchik
patent: WO9631517 (1996-10-01), None
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Cecil Textbook of Medicine, 20th edition i1996), vol. 2, pp. 1992-1996.
FDA mulls drug to slow late-stage Alzheimer's [online], [retrieved on Sep. 23, 2003]. Retrieved from the internet, URL; http:www.cnn com120031HEALTHIconditionslO91241alzheimers.drug.aplindex.html>.
Cognitive disorder [online], [retrieved on Sep. 1, 2006]. Retrieved from the Internet, URL; http://en.wikipedia.org/wiki/Category:Cognitive—disorders>.
Dementia [online], [retrieved on May 24, 2007]. Retrieved from the Internet, URL; http:llen.wikipedia.orglwikilDementia>.
John Tellew, “Small Molecule Antagonists of the Corticotropin Releasing Factor (CRF) . . . ” Current Topics in Medicinal Chemistry 8:506-520, 2008.
Meena Patel, “Synthesis of 4,5-Diaryl-1 H-pyrazole-3-ol Derivatives as Potential COX-2 Inhibitors” J. Org. Chem. 69:7058-7065, 2004.

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