Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2008-01-29
2008-01-29
Russel, Jeffrey Edwin (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C562S621000, C562S623000
Reexamination Certificate
active
07323448
ABSTRACT:
Compounds of formula (I) or a pharmaceutically or veterinarily acceptable salts thereofwherein R1represents hydrogen, C1-C6alkyl or C1-C6alkyl substituted by one or more halogen atoms; R2represents a group R10-(ALK)m-, and A represents (i) a group of formula (IA):wherein the compounds inhibit the activity of bacterial PDF enzyme.
REFERENCES:
patent: 3166587 (1965-01-01), Bernstein et al.
patent: 3692787 (1972-09-01), Roth et al.
patent: 4996358 (1991-02-01), Handa et al.
patent: 5962666 (1999-10-01), Lonetto
patent: 6045795 (2000-04-01), Ulevitch et al.
patent: 6423690 (2002-07-01), Hunter et al.
patent: 6441042 (2002-08-01), Hunter et al.
patent: 6787522 (2004-09-01), Hunter et al.
patent: 6908911 (2005-06-01), Hunter et al.
patent: 33 20 175 (1984-12-01), None
patent: 082088 (1983-06-01), None
patent: 236872 (1987-09-01), None
patent: 863152 (1998-09-01), None
patent: 879879 (1998-11-01), None
patent: WO 94/07527 (1994-04-01), None
patent: WO 94/10990 (1994-05-01), None
patent: WO 95/32944 (1995-12-01), None
patent: WO 96/16027 (1996-05-01), None
patent: WO 97/38705 (1997-10-01), None
patent: WO 98/38179 (1998-09-01), None
Y Jin et al.: “Inhibition stereochemistry of hydroxamate inhibitors for thermolysin”, Bioorganic & Medicinal Chemistry Letters, vol. 8, No. 24, 1998, pp. 3515-3518, XP002106374.
M-C Fournie-Zaluski et al.: “New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties” Journal of Medicinal Chemistry, vol. 28, No. 9, 1985, pp. 1158-1169, XP002019770.
H.N. Weller, et al.: “Design of conformality Constrained Angiotensin-Converting Enzyme Inhibitors” Biochemical and Biophysical Research Communications, vol. 125, No. 1, 1984, pp. 82-89, XP002106375.
D. Mazel et al.: “Genetic Characteristics of Polypeptide Deformylase, A Distinctive Enzyme of Eubacterial Translation” EMBO, vol. 13, No. 4, pp. 914-923, XP002043973, (1994).
P.T. Ravi Rajagopalan et al.: “Peptide Deformylas: A New Type of Mononuclear Iron Protein”, JAm.Chem.Soc., vol. 119, 1997, pp. 12418-21419, XP002106376.
Beckett Raymond Paul
Clements John Martin
Davies Stephen John
Hunter Michael George
Launchbury Steven
Banner & Witcoff , Ltd.
British Biotech Pharmaceuticals Ltd.
Russel Jeffrey Edwin
LandOfFree
Antibacterial agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibacterial agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibacterial agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2761555