Nucleic acid molecules with specific recognition of native...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C436S006000, C436S091000

Reexamination Certificate

active

07371833

ABSTRACT:
The invention relates to a method for isolating nucleic acid molecules which are capable of specific interaction with native PrPScand can differentiate between native PrPcand native PrPSc. The inventive method comprises the following steps: incubating a pool of nucleic acids with purified PrPScpreparations (PPPs); selecting and isolating the resulting protein
ucleic acid complexes and optionally amplifying the specific nucleic acids, in addition to optionally repeating the incubation and isolation stage. The invention also relates to the nucleic acid molecule produced by this method and the use thereof for diagnosing and treating transmissible spongiform encephalopathies.

REFERENCES:
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