Isoforms of eIF-5A: senescence-induced eLF5A;...

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide encodes an inhibitory rna molecule

Reexamination Certificate

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C800S278000, C800S290000, C536S024500, C435S320100

Reexamination Certificate

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07358418

ABSTRACT:
The present invention relates to unique isoforms of eukaryotic initiation Factor 5A (“eIF-5A”): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase (“DHS”), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.

REFERENCES:
patent: 5328999 (1994-07-01), Bennett et al.
patent: 5530190 (1996-06-01), Grierson et al.
patent: 5763742 (1998-06-01), Morrison et al.
patent: 5767364 (1998-06-01), de Silva et al.
patent: 2002/0023281 (2002-02-01), Gortach et al.
patent: WO 01/02592 (2001-01-01), None
Colliver et al (1997, Plant Mol. Biol. 35:509-522).
Emery et al (2003, Current Biology 13:1768-1774).
Bate, Nichols J. et al., “Expression of Nuclear Chloroplast Photosynthesis-Specific Genes During Leaf Senescence,”Journal of Experimental Botany,vol. 42, No. 239:801-811 (1991).
Bevec, D. et al., “Molecular characterization of cDNA encoding function human deoxyhypusine synthase and chromosomal mapping of the corresponding gene locus,”FEB Lett.,vol. 378:195-198 (1996).
Bevec, Dorian et al., “Eukaryotic Initiation Factor 5A Activity and HIV-1 Rev Function,”Biological Signals,vol. 6:124-133 (1997).
Bird, Colin R. et al., “Manipulation of Plant Gene Expression by Antisense RNA,”Biotechnology and Genetic Engineering Reviews,vol. 9:207-227 (1991).
Bork et al., “Cloning and Expression of the CBL1 Gene Encoding Cystalhionine-Beta-Lyase fromArabidopsis thaliana,” Database EMBL 'Online! Reieved from EBI, Database accession No. AB004823 XP002227363, Jul. 1997.
Bowie et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions”,Science,vol. 247:1306-1310 (1990).
Brach, Marion A., “The Mitogenic Response to Tumor Necrosis Factor Alpha Requires c-Jun/AP-1,”Molecular and Cellular Biology,vol. 13, No. 7:4284-4290 (1993).
Buchanan-Wollaston, Vicky, “The molecular biology of leaf senescence,”Journal of Experimental Botany,vol. 48, No. 307:181-199 (1997).
Chamot, Danuta et al., “Differential expression of genes encoding the hypusine-containing translation initiation factor, eIF-5A in tobacco,”Nucleic Acids Research,vol. 20, No. 4:685-669 (1992).
Chen, Kuang Yu et al., “Biochemistry and Function of Hypusine Formation on Eurkaryotic Initiation Factor 5A,”Biological Signals,vol. 6:105-109 (1997).
Chory, Joanne et al., “A Role for Cytokinins in De-Etiolation in Arabidopsis, del Mutants Have an Altered Response to Cytokinins,”Plant Physiol.,vol. 104:339-347 (1994).
Cohen, Seymore S., “Growth of Studies on Hypusine in Biological Systems,”Biol Signals,vol. 6:110-114 (1997).
Corpet, Florence, “Multiple sequence alignment of hierarchical clustering,” Nucleic Acids Research, vol. 16, No. 22:10880-10890 (1988).
Database Geneseq ′Online!, “Arabidopsis thaliana expressed polynucleotide SEQ ID NO 886,” XP002319520, retrieved from EBI accession No. GSN:ABN99118, Abstract (Aug. 1, 2002).
Dresselhaus et a., “A transcript ancoding translation initiation factor elf-5a is stored in unfertilized egg cells of maize,”Plant Molecular Biology,vol. 39:1063-1071 (1999).
Evans, Philip T. et al., “Do Polyamines Have Roles in Plant Development,”Annu. Rev. Plant Physiol. Plant Mol. Biol.,vol. 40:235-269 (1989).
Fobert, Pierre R et al., “T-DNA tagging of a seed coat-specific cryptic promoter in tobacco,”The Plant Journal,ol. 6, No. 4:567-577 (1994).
Fourgoux-Nicol et al., “Isolation of rapeseed genes expressed early and specifically during developement of the male gametophyte,”Plant Molecular Biology,vol. 40:857-872 (1999).
Fromm, Michael E. et al., “Stable transformation of maize after gene transfer by electroporation,”Letters To Nature,vol. 319:791-793 (1986).
Gallie, Daniel R., “A tale of two termi: A functional interaction between the termini of an mRNA is a prerequisite for efficient translation initiation,”Gene, vol. 216:1-11 (1998).
Galston, Arthur W. et al., “Polyamines in Plant Physilogy1,”Plant Physiol.,vol. 94:406-410 (1990).
Gan, Susheng et al., “Making Sense of Senescence1,”Plant. Physiol.,vol. 113:313-319 (1997).
Goyns, M. H., “The Role of Polyamines in Animal Cell Physiology,”J. theor. Biol.,vol. 97:577-589 (1982).
Hensel, Linda L. et al., “Developmental and Age-Related Processes The Influence the Longevity and Senescence of Photosynthetic Tissues in Arabidopsis,”The Plant Cell,vol. 5:553-564 (1993).
Igarashi, Kazuei et al., “Increase of Fidelity of Polypeptide Synthesis by Spermidine in Eukarytoc Cell-Free Systems,”Eur. J. Biochem,vol. 128:597-604 (1982).
Joe, Young Ae et al., “Cloning and Expression of Human Deoxyhypusine Synthase cDNA: Structure-Function Studies with the Recombinant Enzyme and Mutant Proteins,”The Journal of Biological Chemistry, vol. 270, No. 38:22386-22392 (1995).
Klein, T. M. et al., “Factors Influencing Gene Delivery into Zea Mays Cells by High-Velocity Microprojectiles,”Bio/Technology, vol. 6:559-563 (1988).
Kuipers, Anja G.J. et al., “Factors affecting the inhibition of antisense RNA of granule-bound starch synthase gene expression in potato,”Mol Gen Genet, vol. 246:745-755 (1995).
Merlo, Ann Owens et al., “Robozymes Targeted to Stearoyl-ACP Δ9 Desaturase mRNA Produce Heritable Increases of Stearic Acid in Transgenic Maize Leaves,”The Plant Cell,vol. 10:1603-1621 (1998).
Miki, B. L. et al., “Procedures for Introducing Foreign DNA into Plants,”CRC Press Inc.pp. 67-88 (1993).
Moonan, F. et al., “Analyses of Genotypic Diversity among North, South, and Central American Isolates of Sugarcane Yellow Leaf Virus: Evidence for Columbian Origins and for Intraspecific Spatial Phylogenetic Variation,”Journal of Virology, vol. 76:1339-1348 (2002).
Morton, R. et al., “Gene Replacement,”Molecular Breeding,vol. 1:123-132 (1995).
Murphey, Roberta J. et al., “Hypusine Formation in Protein by a Two-step Process in Cell Lysates,”The Journal of Biological Chemistry, vol. 262, No. 31:15033-15036 (1987).
Murphey, Roberta J. et al., “Hypusine Biosynthesis in Protein and its Biological Consequences,”Proceedings of the International Symposium on Polyamines in Biochemical and Clinical Researchpp. 449-458 (1988).
Nierlich, Donald P. et al., “Molecular Mechanisms in the Control of Gene Expression,”ICN-UCLA Sumposia on Molecular and Cellular Biology, vol. 5 (1976).
Ober et al., “Deoxyhypusine Synthase from Tobacco: cDNA Isolation, Characterization, and Bacterial Expression of an Enzyme with Extended Substrate Specificity” 1999,Journal of Biological Chemistry274:32040-32047.
Palauqui, Jean-Christophe et al., “Frequencies, Timing, and Spatial Patterns of Co-Suppression of Nitrate Reductase and Nitrite Reductase in Transgenic Tobacco Plants1,”Plant Physiol., vol. 112:1447-1456 (1996).
Park, Myung Hee et al., “Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and a spermidine as its biosynthetic precursor,”Proc. Natl. Acad. Sci. USA, vol. 78, No. 5:2869-2873 (1981).
Park, Myung Hee et al., “The Biosynthesis of Protein-bound Hypusine (Ne-(4-Amino-2-hydroxybutyl)lysine); Lysine as the Amino Acid Precursor and the Intermediate Role of Deoxyhypusine (Ne-(4-Amino-2-hydroxybutyl)lysine),”The Journal of Biological Chemistry,vol. 257, No. 12:7217-7222 (1982).
Park, Myung Hee et al., “The Biosynthesis of Hypusine (Ne-(4-Amino-2-hydroxybutyl)lysine); Alignment of the Butylamine Segment and Source of the Secondary Amino Nitr

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