Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-01-29
2008-01-29
Forman, BJ (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S283100, C435S287200, C536S023100
Reexamination Certificate
active
07323298
ABSTRACT:
A method of determining the relative amounts of individual polynucleotides in a complex mixture of different-sequence polynucleotides is disclosed. The polynucleotides, after fluorescent labeling, are contacted under hybridization conditions with an array of different DNA sequences disposed at discrete locations on a non-porous surface, at an array density of at least about 100 sequences/cm2, where the different DNA sequences in the array are effective to hybridize to individual polynucleotides in the mixture. The level of fluorescence associated with each array sequence provides a measure of its relative amount in the mixture.
REFERENCES:
patent: 3730844 (1973-05-01), Gilham et al.
patent: 3849137 (1974-11-01), Barzynski et al.
patent: 4071315 (1978-01-01), Chateau
patent: 4269933 (1981-05-01), Pazos
patent: 4327073 (1982-04-01), Huang
patent: 4483920 (1984-11-01), Gillespie et al.
patent: 4486539 (1984-12-01), Ranki et al.
patent: 4516833 (1985-05-01), Fusek
patent: 4517338 (1985-05-01), Urdea et al.
patent: 4537861 (1985-08-01), Elings et al.
patent: 4556643 (1985-12-01), Paau et al.
patent: 4562157 (1985-12-01), Lowe et al.
patent: 4563419 (1986-01-01), Ranki et al.
patent: 4591570 (1986-05-01), Chang
patent: 4613566 (1986-09-01), Potter
patent: 4631211 (1986-12-01), Houghten
patent: 4670380 (1987-06-01), Dattagupta
patent: 4677054 (1987-06-01), White et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4689405 (1987-08-01), Frank et al.
patent: 4704353 (1987-11-01), Humphries et al.
patent: 4711955 (1987-12-01), Ward et al.
patent: 4713326 (1987-12-01), Dattagupta et al.
patent: 4716106 (1987-12-01), Chiswell
patent: 4728502 (1988-03-01), Hamill
patent: 4731325 (1988-03-01), Palva et al.
patent: 4755458 (1988-07-01), Rabbani et al.
patent: 4762881 (1988-08-01), Kauer
patent: 4767700 (1988-08-01), Wallace
patent: 4811062 (1989-03-01), Tabata et al.
patent: 4820630 (1989-04-01), Taub
patent: 4833092 (1989-05-01), Geysen
patent: 4846552 (1989-07-01), Veldkamp et al.
patent: 4868103 (1989-09-01), Stavrianopoulos et al.
patent: 4868104 (1989-09-01), Kurn et al.
patent: 4868105 (1989-09-01), Urdea et al.
patent: 4874500 (1989-10-01), Madou et al.
patent: 4877745 (1989-10-01), Hayes et al.
patent: 4921805 (1990-05-01), Gebeyehu et al.
patent: 4923901 (1990-05-01), Koester et al.
patent: 4925785 (1990-05-01), Wang et al.
patent: 4946942 (1990-08-01), Fuller et al.
patent: 4981783 (1991-01-01), Augenlicht
patent: 4981985 (1991-01-01), Kaplan et al.
patent: 4984100 (1991-01-01), Takayama et al.
patent: 4987065 (1991-01-01), Stavrianopoulos et al.
patent: 4988617 (1991-01-01), Landegren et al.
patent: 4994373 (1991-02-01), Stavrianopoulos et al.
patent: 5013669 (1991-05-01), Peters, Jr. et al.
patent: 5028545 (1991-07-01), Soini
patent: 5043265 (1991-08-01), Tanke et al.
patent: 5064754 (1991-11-01), Mills
patent: 5082830 (1992-01-01), Brakel et al.
patent: 5091652 (1992-02-01), Mathies et al.
patent: 5100777 (1992-03-01), Chang
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5185243 (1993-02-01), Ullman et al.
patent: 5188963 (1993-02-01), Stapleton
patent: 5200051 (1993-04-01), Cozzette et al.
patent: 5200312 (1993-04-01), Oprandy
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5204268 (1993-04-01), Matsumoto
patent: 5215882 (1993-06-01), Bahl et al.
patent: 5232829 (1993-08-01), Longiaru et al.
patent: 5242974 (1993-09-01), Holmes
patent: 5252296 (1993-10-01), Zuckerman et al.
patent: 5252743 (1993-10-01), Barrett et al.
patent: 5258506 (1993-11-01), Urdea et al.
patent: 5328824 (1994-07-01), Ward et al.
patent: 5338688 (1994-08-01), Deeg et al.
patent: 5348855 (1994-09-01), Dattagupta et al.
patent: 5389512 (1995-02-01), Kwok et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5434049 (1995-07-01), Okano et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5447841 (1995-09-01), Gray et al.
patent: 5451683 (1995-09-01), Barrett et al.
patent: 5472842 (1995-12-01), Stokke et al.
patent: 5474796 (1995-12-01), Brennan
patent: 5474895 (1995-12-01), Ishii et al.
patent: 5486452 (1996-01-01), Gordon et al.
patent: 5489507 (1996-02-01), Chehab
patent: 5510270 (1996-04-01), Fodor et al.
patent: 5512430 (1996-04-01), Gong
patent: 5514543 (1996-05-01), Grossman et al.
patent: 5514785 (1996-05-01), Van Ness et al.
patent: 5516641 (1996-05-01), Ullman et al.
patent: 5518883 (1996-05-01), Soini
patent: 5545531 (1996-08-01), Rava et al.
patent: 5556748 (1996-09-01), Douglas
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5563060 (1996-10-01), Hozier
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5605662 (1997-02-01), Heller et al.
patent: 5665549 (1997-09-01), Pinkel et al.
patent: 5677195 (1997-10-01), Winkler et al.
patent: 5700637 (1997-12-01), Southern
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5795716 (1998-08-01), Chee et al.
patent: 5800992 (1998-09-01), Fodor et al.
patent: 5830645 (1998-11-01), Pinkel et al.
patent: 5985551 (1999-11-01), Brennan
patent: 6013449 (2000-01-01), Hacia et al.
patent: 6045996 (2000-04-01), Cronin et al.
patent: 6171843 (2001-01-01), Bandman et al.
patent: 0 063 810 (1982-11-01), None
patent: 0 171 150 (1986-02-01), None
patent: 0 235 726 (1987-09-01), None
patent: 0 281 927 (1988-09-01), None
patent: 0 337 498 (1989-10-01), None
patent: 0 337 498 (1989-10-01), None
patent: 0717113 (1996-06-01), None
patent: 721016 (1996-07-01), None
patent: 2248840 (1993-01-01), None
patent: 59-24244 (1984-02-01), None
patent: 63-223557 (1988-09-01), None
patent: WO 84/03151 (1984-08-01), None
patent: WO89/10977 (1989-05-01), None
patent: WO 89/11548 (1989-11-01), None
patent: WO90/03382 (1990-04-01), None
patent: WO92/10588 (1992-06-01), None
patent: WO 93/09668 (1993-05-01), None
patent: WO93/22680 (1993-11-01), None
patent: WO95/00530 (1995-01-01), None
patent: WO 95/11995 (1995-05-01), None
patent: WO95/15970 (1995-06-01), None
patent: WO95/21944 (1995-08-01), None
patent: WO95/25116 (1995-09-01), None
patent: WO96/17958 (1996-06-01), None
patent: WO 97/10365 (1997-03-01), None
patent: 18617/87-P-570/87 (1988-02-01), None
patent: P-570/87 (1988-02-01), None
Billings et al., “New Techniques for Physical Mapping of the Human Genome,”FASEB, 5:28-34 (1991).
Chee, et al., “Accessing Genetic Information with High-Density DNA Arrays”,Science, 274:610-614 (1996).
Drmanac et al., “DNA Sequence Determination by Hybridization: A Strategy for Efficient Large-Scale Sequencing,”Science, 260:1649-1652 (1993).
Drmanac et al., “Laboratory Methods: Reliable Hybridization of Oligonucleotides as Short as Six Nucleotides,”DNA and Cell Biology, 9:527-534 (1990).
Drmanac et al., “Sequencing by Hybridization: Towards an Automated Sequencing of One Million M13 Clones Arrayed on Membrances,”Electrophoresis, 13:566-573 (1992).
Ekins, et al., “Multianalyte Immunoassay: The Immunological ‘Compact Disk’ of the Future”,J. Clinical Immunassay, 13(4);169-181 (1990).
Fodor et al., “Light-Directed, Spatially Addressable Parallel Chemical Synthesis,”Science, 251:767-773 (1991).
Guo, et al., “Direct Fluorescence Analysis of Genetic Polymorphisms by Hybridization with Oligonucleotide Arrays on Glass Supports”,Nucleic Acids Research, 22:5456-5465 (1994).
Johnston, et al., “Chemistry of High Density Arrays: Factors Impacting Issues of Complexity”, (Abstract)Microbial&Comparative Genomics, 1:235 (1996).
Kallioniemi et al., “Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors,”Science, 258:818-821 (1992).
Kallioniemi et al., “Optimizing Comparative Genomic Hybridization for Analysis of DNA Sequence Copy Number Changes in Solid Tumors,”Genes, Chromosomes&Cancer, 10:231-243 (1994).
Khrapko et al., “A Method for DNA Sequencing by Hybridization with Oligonucleotide Matrix,”DNA Sequencing and Mapping, 1:375-388 (1991).
Kozal, et al., “Extensive Polymorphisms Observed in HIV-1 Clade B Protease Gene using
Brown Patrick O.
Shalon Tidhar Dari
Forman BJ
Howrey LLP
The Board of Trustees of the Leland Stanford Junior University
LandOfFree
Microarray for determining the relative abundances of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Microarray for determining the relative abundances of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microarray for determining the relative abundances of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2754372