Hydrate for medical purposes

Details Hydrate for medical purposes Hydrate for medical purposes

2011-08-23

2011-08-23

Seaman, D (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S156000

Reexamination Certificate

active

08003666

ABSTRACT:
The present invention relates to [7-[(7S)-7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-8-methoxy-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hemihydrate. This hemihydrate is stable and easy to prepare, and has excellent properties for a pharmaceutical bulk powder.

REFERENCES:
patent: 5587386 (1996-12-01), Hayakawa et al.
patent: 6900225 (2005-05-01), Takemura et al.
patent: 7563805 (2009-07-01), Takahashi et al.
patent: 2 231475 (1990-09-01), None
patent: 2002 255962 (2002-09-01), None
patent: 2005-146386 (2005-05-01), None
patent: 2003/076428 (2003-09-01), None
patent: 2006 123767 (2006-11-01), None
patent: 2006 123792 (2006-11-01), None
patent: WO 2006/123792 (2006-11-01), None
Bozdogan, J Antimicrobial Chemotherapy, vol. 52, pp. 864-868, 2003.

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