Method of forming bioabsorbable drug delivery devices

Plastic and nonmetallic article shaping or treating: processes – Forming continuous or indefinite length work – Layered – stratified traversely of length – or multiphase...

Reexamination Certificate

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C264S209100, C264S211000

Reexamination Certificate

active

07927529

ABSTRACT:
A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, hereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes. The solid ladder configuration provides increased radiopacity and increased radial strength, whereas the open lattice configuration provides better endothelialization and fluid flow through the stent. The drug or other agent delivery capacity of the devices may provide local or regionalized drug or other agent delivery, or a combination thereof, with more consistent concentrations of drugs or other agents delivered from the device to the treatment site along the entire length of the device.

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