Tripeptides and derivatives thereof for cosmetic application...

Details Tripeptides and derivatives thereof for cosmetic application... Tripeptides and derivatives thereof for cosmetic application...

2011-01-04

2011-01-04

Lukton, David (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Tripeptides, e.g., tripeptide thyroliberin , etc.

C514S018700

Reexamination Certificate

active

07863417

ABSTRACT:
The invention relates to compounds and to the cosmetically acceptable salts thereof, which correspond to general formula (I), wherein: R1represents H, —C(O)—R6, —SO2—R6or —C(O)—XR6; R2and R4, independent of one another, represent (CH2)n—NH2or (CH2)3—NHC(NH)NH2; n equals 1 4; R3represents linear or branched C1-C4alkyl that is optionally substituted by hydroxy; R5and R6, independent of one another, represent hydrogen, optionally substituted (C1-C24) alkyl, optionally substituted C2-C24alkenyl, optionally substituted phenyl, optionally substituted phenyl-C1-C4alkyl or 9-fluorenyl-methyl; X represents oxygen (—O—) or —NH—; or XR5with X═O also represents the esters of a-tocopherol, tocotrienol or retinol, with the provision that R1and R5do not represent hydrogen and X does not represent oxygen at the same time. The invention also relates to the production of the compounds of general formula (I) and to a cosmetically active composition that contains at least one compound of formula (I).

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International Search Report for PCT/CH2004/000278, mailed Aug. 2, 2004.

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