Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2011-03-08
2011-03-08
Cordero Garcia, Marcela M (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S003400
Reexamination Certificate
active
07902148
ABSTRACT:
This invention is directed to methods of administering an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent having a substituent comprising at least about 8 carbon atoms. The invention is also directed to methods of using an echinocandin antifungal agent in combination with a specified glycopeptide antibacterial agent to treat fungal infections; and to compositions, kits and systems comprising an echinocandin antifungal agent and a specified glycopeptide antibacterial agent.
REFERENCES:
patent: 5378804 (1995-01-01), Balkovec et al.
patent: 5840684 (1998-11-01), Cooper et al.
patent: 5925616 (1999-07-01), Whittemore
patent: 6107458 (2000-08-01), Ohki et al.
patent: 6267979 (2001-07-01), Raad et al.
patent: 6635618 (2003-10-01), Leadbetter et al.
patent: 6719991 (2004-04-01), Darouiche et al.
patent: 6743777 (2004-06-01), Burkhardt et al.
patent: 7452861 (2008-11-01), Kaniga
patent: 7521418 (2009-04-01), Kaniga
patent: 2003/0017975 (2003-01-01), Ikeda et al.
patent: 0525499 (1993-02-01), None
patent: 0667353 (1995-08-01), None
patent: 97/36479 (1997-10-01), None
patent: 00/72865 (2000-12-01), None
Ghanoum et al. Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance. Clinical Microbiology Reviews. Oct. 1999, vol. 12, No. 4, pp. 501-517.
Bouffard et al. Synthesis and Antifungal Activity of Novel Cationic Penumocandin Bo Derivatives. J Med Chem 1994, vol. 37, pp. 222-225.
Petraitiene et al. Antifungal Activity of LY303366, a Novel Echinocandin B, in Examperiment Disseminated Candidiasis in Rabbits. Antimiccrobial Agents and Chemotherapy, Sep. 1999, vol. 43, Nol. 9, pp. 2148-2155.
Arikan et al., “New agents for the treatment of systemic fungal infections-current status”, Expert Opin. Emerging Drugs, 7(1), pp. 3-32 (2002).
Boger, “Vancomycin, Teicoplanin and Ramoplanin”, Medicinal Research Reviews, 2001, 21(5), pp. 356-381.
Chiou et al., “Synergy, Pharmacodynamics, and Time-Sequenced Ultrastructural Changes of the Interaction between Nikkomycin Z and the Echinocandin FK463 againstAspergillus fumigatus”, Antimicrobial Agents and Chemotherapy, vol. 45, No. 12, pp. 3310-3321 (2001).
Denning, “Echinocandins:a new class of antifungal”, Journal of Antimicrobial Chemotherapy, 49, pp. 889-891 (2002).
Denning, “Echinocandin antifungal drugs”, The Lancet, vol. 362, pp. 1142-1151 (2003).
Eliopoulos et al., “Antimicrobial Combinations”, Antibiotics in Laboratory Medicine, 4th Edition, Williams & Wilkins, pp. 330-396 (1996).
Ge et al., “Vancomycin Derivatives That Inhibit Peptidoglycan Biosynthesis Without Binding D-Ala-D-Ala”, Science, Apr. 16, 1999, vol. 284, pp. 507-511.
Giglione et al., “The Situation on Antimicrobial Agents and Chemotherapy in 2002: Highlights of the 42nd ICAAC, Sep. 27-30, 2002, San Diego, USA”, Expert Opinion Therapeutic Targets, 2002, 6(6), pp. 691-697.
Groll et al., “Caspofungin:pharmacology, safety and therapeutic potential in superficial and invasive fungal infections”, Expert Opin. Investig. Drugs, 10(8), pp. 1545-1558 (2001).
Hossain et al., “New investigational antifungal agents for treating invasive fungal infections”, Expert Opin. Invest. Drugs, 9(8), pp. 1797-1813 (2000).
Kureishi et al., “Double-blind comparison of teicoplanin versus vancomycin in febrile neutropenic patients receiving concomitant tobramycin and piperacillin: Effect on cyclosporine A-associated nephrotoxicity”, Antimicrobial Agents and Chemotherapy, vol. 35 No. 11, pp. 2246-2252 (Nov. 1991).
Lacroix, C., et al., “Echinocandins: a new class of antifungal agents”, Medicine et maladies infectieuses, 33 (4):183-191, Apr. 2003. (in French with English abstract).
Lewis et al., “Rationale for Combination Antifungal Therapy”, Pharmacotherapy, vol. 21, No. 8, pp. 149s-164s (2001).
Link, H., “Antimicrobial prophylaxis and therapy in neutropenia”, Mycoses 46(Suppl. 2):21-32, Feb. 2003. (in German with English abstract).
Manavathu et al., “Differential activity of triazoles in two-drug combinations with the echinocandin caspofungin againstAspergillus fumigatus”, J. of Antimicrobial Chemotherapy, 51, pp. 1423-1425 (2003).
Nicolaou et al., “Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics”, Angew. Chem. Int. Ed., 38, pp. 2096-2152 (1999).
Office Action in U.S. Appl. No. 10/854,575, dated Nov. 24, 2006.
Office Action in U.S. Appl. No. 10/854,575, dated Apr. 27, 2007.
Office Action in U.S. Appl. No. 10/854,575, dated Aug. 6, 2007.
Pace, John L., “TD-6424: A novel multifunctional antibiotic”, Abstr Intersci Conf Antimicrob Agents Chemother, 42: Abstract No. 614, Sep. 27-30, 2002.
Preobrazhenskaya, M. and Olsufyeva, E., “Patents on glycopeptides of the vancomycin family and their derivatives as antimicrobials: Jan. 1999-Jun. 2003”, Expert Opin. Ther. Patents, 14(2):141-173, 2004.
Shalit et al., “In Vitro Synergy of Caspofungin and Itraconazole againstAspergillusspp.: MIC versus Minimal Effective Concentration End Points”, Antimicrobial Agents and Chemotherapy, vol. 47, No. 4, pp. 1416-1418 (2003).
Sugar, “Overview: Antifungal combination therapy”, Current Opinion in Investigational Drugs, 2(10), pp. 1364-1365 (2001).
Taccone F.S., et al., Caspofungin salvage therapy in a neutropenic patient with probable invasive aspergillosis: a case report, Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer, 11 (11):742-744, Nov. 2003.
Vanden Bossche, “Echinocandins—an update”, Expert Opin. Ther. Patents, 12(2), pp. 151-167 (2002).
Cony-Makhoul et al., “A prospective study comparing vancomycin and teicoplanin as second-line empiric therapy for infection in neutropenic patients”, British Journal of Haematology, 1990, 76, Suppl. 2, pp. 35-40.
Rossi et al., “Aspergillus fumigatusinfections in liver transplant patients”, Transplantation Proceedings, vol. 21, No. 1 (Feb. 1989), pp. 2268-2270.
Cordero Garcia Marcela M
Hagenah Jeffrey A.
Theravance Inc.
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